Brain Extract Total

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Category	Extracts
Catalog NO.	BPG-3248
Product Name	Brain Extract Total
CAS	86088-88-2

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Product Information

Description	Brain Extract Polar comprises phosphatidylethanolamine as major lipid component. It also contains phosphatidylserine and phosphatidylcholine. The minor components include the phosphatidic acid and phosphatidylinositol. Brain lipid, especially the polar fraction plays a key role in the inhibition of prion seeded amyloid formation. Lipid extracts from the mammalian tissues like brain, kidney and liver are used in generating model membranes for mimicking real membranes.
Synonyms	Brain Total Lipid Extract (Porcine)
Purity	>99%
Appearance	Powder
Shelf Life	1 Year
Storage	Store at -20°C
Hygroscopic	Yes
Light Sensitive	No

References

1. Campello L, Kutsyr O, Noailles A, Michalska P, Fernández-Sánchez L, Martínez-Gil N, Ortuño-Lizarán I, Sánchez-Sáez X, de Juan E, Lax P, León R, García AG, Cuenca N, Maneu V. New Nrf2-Inducer Compound ITH12674 Slows the Progression of Retinitis Pigmentosa in the Mouse Model rd10. Cell Physiol Biochem. 2020 Feb 7;54(1):142-159. doi: 10.33594/000000210. PMID: 32028545. PubMed ID: 32028545.
2. Liou AY, Molday LL, Wang J, Andersen JP, Molday RS. Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells. J Biol Chem. 2019 Mar 8. pii: jbc.RA118.007270. doi: 10.1074/jbc.RA118.007270. [Epub ahead of print]...PubMed ID: 30850395.
3. Chen Y, Wu B, Hao Y, Liu Y, Zhang Z, Tian C, Ning X, Guo Y, Liu J, Wang X. Structure-activity relationship studies of (E)-3,4-dihydroxystyryl alkyl sulfones as novel neuroprotective agents based on improved antioxidant, anti-inflammatory activities and BBB permeability. Eur J Med Chem. 2019 Jun 1;171:420-433. doi: 10.1016/j.ejmech.2019.03.044. Epub 2019 Mar 21. PubMed ID: 30928712.
4. Milite C, Feoli A, Horton JR, Rescigno D, Cipriano A, Pisapia V, Viviano M, Pepe G, Amendola G, Novellino E, Cosconati S, Cheng X, Castellano S, Sbardella G. Discovery of a Novel Chemotype of Histone Lysine Methyltransferase EHMT1/2 (GLP/G9a) Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Co-crystal Structure. J Med Chem. 2019 Mar 14;62(5):2666-2689. doi: 10.1021/acs.jmedchem.8b02008. Epub 2019 Feb 26. PubMed ID: 30753076.
5. Sang Z, Wang K, Han X, Cao M, Tan Z, Liu W. Design, Synthesis, and Evaluation of Novel Ferulic Acid Derivatives as Multi-Target-Directed Ligands for the Treatment of Alzheimer's Disease. ACS Chem Neurosci. 2019 Feb 20;10(2):1008-1024. doi: 10.1021/acschemneuro.8b00530. Epub 2019 Jan 4. PubMed ID: 30537804.
6. Becher S, Esch P, Heiles S. Relative Quantification of Phosphatidylcholine sn-Isomers Using Positive Doubly Charged Lipid-Metal Ion Complexes. Anal Chem. 2018 Sep 21. doi: 10.1021/acs.analchem.8b02731. [Epub ahead of print]...PubMed ID: 30199242.

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