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Bis-PEG7-sulfonic acid

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Category Bis-PEGn-sulfonic acid
Catalog NO. BPG-1250
Product Name Bis-PEG7-sulfonic acid
Molecular Formula C16H34O13S2
Molecular Weight 498.54
Bis-PEG7-sulfonic acid
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Product Information

Description Bis-PEG7-sulfonic acid is a PEG linker containing sulfonic acid moieties. Sulfonic acid can participate in esterification, halogenation and displacement reactions. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
Synonyms 3,6,9,12,15,18,21-heptaoxatricosane-1,23-disulfonic acid
IUPAC Name 2-[2-[2-[2-[2-[2-[2-(2-sulfoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanesulfonic acid
Canonical SMILES O=S(CCOCCOCCOCCOCCOCCOCCOCCS(=O)(O)=O)(O)=O
InChI InChI=1S/C16H34O13S2/c17-30(18,19)15-13-28-11-9-26-7-5-24-3-1-23-2-4-25-6-8-27-10-12-29-14-16-31(20,21)22/h1-16H2,(H,17,18,19)(H,20,21,22)
InChIKey OQHQIBZQUJZTRK-UHFFFAOYSA-N
Purity ≥95%
Storage Store at 2-8°C

Bis-PEG7-sulfonic acid, a versatile compound with diverse biotechnological applications, plays a pivotal role in various fields. Here are four key applications presented with high perplexity and burstiness:

Protein Stabilization: Widely utilized for enhancing protein stability in solution, Bis-PEG7-sulfonic acid acts as a safeguard against protein aggregation and denaturation. By preserving protein functionality within therapeutic formulations, it proves instrumental in developing injectable protein-based drugs, ensuring their efficacy and reliability in clinical settings.

Drug Delivery: Within the realm of drug delivery, Bis-PEG7-sulfonic acid emerges as a transformative agent, enhancing the solubility and bioavailability of hydrophobic drugs. Serving as a solubilizing agent, it facilitates the formulation of otherwise challenging-to-administer drugs, leading to improved therapeutic outcomes and streamlined treatment regimens, marking a significant advancement in pharmaceutical delivery strategies.

Surface Coating: In the domain of surface coating applications, Bis-PEG7-sulfonic acid is harnessed to imbue hydrophilic properties onto diverse materials. By employing this compound to coat medical devices and implants, it effectively reduces protein adsorption and cell adhesion, thereby mitigating foreign body responses and enhancing the devices' biocompatibility, ensuring safe and efficient integration within biological systems.

Analytical Chemistry: A critical component in analytical chemistry, Bis-PEG7-sulfonic acid serves as a surfactant in capillary electrophoresis and other separation techniques. By enhancing separation efficiency and resolution of biomolecules through the reduction of electrostatic interactions, it enables accurate and precise analytical measurements in research and diagnostic settings, facilitating advancements in scientific analysis and discovery.

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