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Bis-PEG7-acid

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Category Small-molecule Homobifunctional PEG
Catalog NO. BPG-2132
Product Name Bis-PEG7-acid
CAS 94376-75-7
Molecular Formula C18H34O11
Molecular Weight 426.46
Bis-PEG7-acid
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Product Information

Description Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms 4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid; HOOCCH2CH2O-PEG6-CH2CH2COOH; α,ω-Dipropionic acid hexaethylene glycol; 4,7,10,13,16,19,22-Heptaoxapentacosane-1,25-dioic acid
IUPAC Name 3-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES C(COCCOCCOCCOCCOCCOCCOCCC(=O)O)C(=O)O
InChI InChI=1S/C18H34O11/c19-17(20)1-3-23-5-7-25-9-11-27-13-15-29-16-14-28-12-10-26-8-6-24-4-2-18(21)22/h1-16H2,(H,19,20)(H,21,22)
InChIKey AYUREXAVZVVOJM-UHFFFAOYSA-N
Boiling Point 572.8±50.0 °C at 760 mmHg
Purity ≥95%
Density 1.186±0.06 g/cm3
Solubility Soluble in DMSO
Related CAS 51178-68-8 (polymer)
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
Exact Mass 426.2101119
LogP 0.05200

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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