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Bis-PEG4-acid

CAS No. CAS No.: 31127-85-2
Cat No. Cat No.: BPG-1906
Purity Purity: >95%
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Bis-PEG4-acid is a PEG PROTAC linker. Bis-PEG4-acid is a PEG derivative containing two terminal carboxylic acid groups. The terminal carboxylic acids can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Category COOH-PEGn-COOH
Molecular Formula C12H22O8
Molecular Weight 294.30
Appearance Pale Yellow or Colorless Oily Matter
Shipping Room temperature in continental US; may vary elsewhere
Storage Store at 2-8°C
Bis-PEG4-acid

Structure of 31127-85-2

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  • Specification
Synonyms 4,7,10,13-Tetraoxahexadecane-1,16-dioic acid; 4,7,10,13-tetraoxahexadecanedioic acid; HOOCCH2CH2O-PEG3-CH2CH2COOH; α,ω-Dipropionic acid triethylene glycol; 4,7,10,13-Tetraoxa-hexadecan-1,16-dicarbonsaeure
IUPACName 3-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
CanonicalSMILES C(COCCOCCOCCOCCC(=O)O)C(=O)O
InChI InChI=1S/C12H22O8/c13-11(14)1-3-17-5-7-19-9-10-20-8-6-18-4-2-12(15)16/h1-10H2,(H,13,14)(H,15,16)
InChIKey LGEVPLDBBPWJIC-UHFFFAOYSA-N
BoilingPoint 483.7±45.0 °C at 760 mmHg
Purity >95%
Density 1.219±0.06 g/cm3 (Predicted)
Solubility Soluble in DCM, DMF, DMSO, Water
RelatedCAS 51178-68-8 (polymer)
ExactMass 294.13146766
LogP 0.00220

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