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Bis-PEG3-NHS Ester

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Category Bis-PEGn-NHS ester
Catalog NO. BPG-3568
Product Name Bis-PEG3-NHS Ester
CAS 1314378-16-9
Molecular Formula C18H24N2O11
Molecular Weight 444.39
Bis-PEG3-NHS Ester
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Product Information

Description Bis-PEG3-NHS ester is a non-cleavable 3-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs).
Synonyms α,ω-disuccinimidyl diethylene glycol; bis(2,5-dioxopyrrolidin-1-yl) 3,3'-(2,2'-oxybis(ethane-2,1-diyl)bis(oxy))dipropanoate; 1,1'-Bis(2,5-dioxo-1-pyrrolidinyl) 3,3'-[oxybis(2,1-ethanediyloxy)]bis[propanoate]; Propanoic acid, 3,3'-[oxybis(2,1-ethanediyloxy)]bis-, 1,1'-bis(2,5-dioxo-1-pyrrolidinyl) ester; 1,1'-{Oxybis[2,1-ethanediyloxy(1-oxo-3,1-propanediyl)oxy]}di(2,5-pyrrolidinedione); 2,5-Pyrrolidinedione, 1,1'-[oxybis[2,1-ethanediyloxy(1-oxo-3,1-propanediyl)oxy]]bis-; NHS-PEG3-NHS
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]propanoate
Canonical SMILES C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCC(=O)ON2C(=O)CCC2=O
InChI InChI=1S/C18H24N2O11/c21-13-1-2-14(22)19(13)30-17(25)5-7-27-9-11-29-12-10-28-8-6-18(26)31-20-15(23)3-4-16(20)24/h1-12H2
InChIKey OPGNUERFYQLUNP-UHFFFAOYSA-N
Boiling Point 577.4±60.0°C (Predicted)
Purity ≥98%
Density 1.42±0.1 g/cm3 (Predicted)
Solubility Soluble in DMSO
Related CAS 123502-57-8 (polymer)
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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