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Biotin-PEG4-STP Ester
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| Category | Small-molecule Biotin PEG |
| Catalog NO. | BPG-4468 |
| Product Name | Biotin-PEG4-STP Ester |
| Molecular Formula | C27H37F4N3O11S2 |
| Molecular Weight | 719.7 |
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| Description | Biotin-PEG4-STP Ester (4-Sulfo-2,3,5,6-tetrafluorophenyl ester) is an amine-reactive, water-soluble labeling reagent used to modify proteins, antibodies, and other amine-containing biopolymers in 100% aqueous media. The hydrophilic polyethylene glycol (PEG) spacer arm of this reagent imparts water solubility that is transferred to the labeled molecule, thus reducing aggregation of labeled proteins stored in solution. The PEG spacer arm also gives the reagent a long and flexible connection to minimize steric hindrance involved with binding to avidin molecules. |
| Synonyms | Biotin-PEG4-STP Ester |
| IUPAC Name | 4-[3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoyloxy]-2,3,5,6-tetrafluorobenzenesulfonic acid |
| Canonical SMILES | C1C2C(C(S1)CCCCC(=O)NCCOCCOCCOCCOCCC(=O)OC3=C(C(=C(C(=C3F)F)S(=O)(=O)O)F)F)NC(=O)N2 |
| InChI | InChI=1S/C27H37F4N3O11S2/c28-20-22(30)26(47(38,39)40)23(31)21(29)25(20)45-19(36)5-7-41-9-11-43-13-14-44-12-10-42-8-6-32-18(35)4-2-1-3-17-24-16(15-46-17)33-27(37)34-24/h16-17,24H,1-15H2,(H,32,35)(H2,33,34,37)(H,38,39,40)/t16-,17-,24-/m0/s1 |
| InChIKey | PGIFHQPXCXPBCM-UAVUOLJFSA-N |
| Storage | -20°C |
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Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
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- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
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- Polyethylene Glycol (PEG) Modifier Selection Guide
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Cholesterol: Definition, Structure, Synthesis, Types and Functions
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
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- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What are Sterols? - Definition, Structure, Function, Examples and Uses
- What is Biotinylation and Biotinylated PEG?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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