Biotin-PEG2-acid
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| Category | Biotin PEG |
| Catalog NO. | BPG-2095 |
| Product Name | Biotin-PEG2-acid |
| CAS | 1365655-89-5 |
| Molecular Formula | C17H29N3O6S |
| Molecular Weight | 403.49 |
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| Description | Biotin-PEG2-acid is a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Synonyms | (+)-Biotin-PEG2-acid; (+)-Biotin-PEG2-COOH; 3-(2-(2-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)ethoxy)ethoxy)propanoic acid |
| IUPAC Name | 3-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]propanoic acid |
| Canonical SMILES | C1C2C(C(S1)CCCCC(=O)NCCOCCOCCC(=O)O)NC(=O)N2 |
| InChI | InChI=1S/C17H29N3O6S/c21-14(18-6-8-26-10-9-25-7-5-15(22)23)4-2-1-3-13-16-12(11-27-13)19-17(24)20-16/h12-13,16H,1-11H2,(H,18,21)(H,22,23)(H2,19,20,24)/t12-,13-,16-/m0/s1 |
| InChIKey | SDOAIZRTYJIBBG-XEZPLFJOSA-N |
| Boiling Point | 752.2±60.0 °C at 760 mmHg |
| Flash Point | 408.7±32.9 °C |
| Purity | >98.0% |
| Density | 1.2±0.1 g/cm3 |
| Solubility | 10 mm in DMSO |
| Appearance | Solid |
| Shelf Life | -20℃ 3 years powder; -80℃ 2 years in solvent |
| Storage | -20°C |
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Resources
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Technical Information
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- Introduction of Polyethylene Glycol (PEG)
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
- Applications of Polyethylene Glycol (PEG) as Medical Devices
- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
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- How Lipid Nanoparticles (LNPs) Deliver RNA Drugs?
- Hyaluronic Acid & PEGylated Hyaluronic Acid
- Ionizable Lipids for RNA Delivery
- Lipid Classification and Drug Delivery Systems
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- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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PEG linkers For Drug
Improved Circulation Half-Life
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