Azido-PEG6-amine
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Category | Azido-PEGn-amine |
Catalog NO. | BPG-3553 |
Product Name | Azido-PEG6-amine |
CAS | 957486-82-7 |
Molecular Formula | C14H30N4O6 |
Molecular Weight | 350.41 |
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Description | Azido-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-amine is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
Synonyms | O-(2-Aminoethyl)-O'-(2-azidoethyl)pentaethylene Glycol; N3-PEG6-CH2CH2NH2; 20-azido-3,6,9,12,15,18-hexaoxaicosan-1-amine; N3-PEG6-NH2 |
IUPAC Name | 2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanamine |
Canonical SMILES | C(COCCOCCOCCOCCOCCOCCN=[N+]=[N-])N |
InChI | InChI=1S/C14H30N4O6/c15-1-3-19-5-7-21-9-11-23-13-14-24-12-10-22-8-6-20-4-2-17-18-16/h1-15H2 |
InChIKey | VCQSTKKJKNUQBI-UHFFFAOYSA-N |
Purity | ≥95% |
Solubility | Soluble in DCM, DMF, DMSO, Water |
Appearance | Pale Yellow or Colorless Oily Matter |
Storage | Store at -20°C, keep in dry and avoid sunlight |
Exact Mass | 350.21653469 |
LogP | 0.50806 |
Pictogram(s) | Irritant |
Signal | Warning |
Precautionary Statement Codes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
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Resources
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Technical Information
- Aqueous Two-Phase System (ATPS) Technique
- Capillary Electrophoresis (CE) Technique
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- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
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- PEG for Chemical Synthesis
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- Polyethylene Glycol (PEG) Modifier Selection Guide
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Industry News
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- Applications of Polyethylene Glycol (PEG) as Medical Devices
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- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
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- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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