Azido-PEG6-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane

Name: Azido-PEG6-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	Azido-PEGn-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane
Catalog NO.	BPG-0890
Product Name	Azido-PEG6-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane
Molecular Formula	C40H74N4O16
Molecular Weight	867.03

Azido-PEG6-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane @(data.CAS != null ? $"| CAS " : "") - BOC Sciences

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Description	Azido-PEG6-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a branched PEG derivative with a terminal azide group and three t-butyl esters. The azide group enables PEGylation via Click Chemistry. The t-butyl protected carboxyl groups can be deprotected under mild acidic conditions.
Synonyms	tert-butyl 1-azido-23,23-bis((3-(tert-butoxy)-3-oxopropoxy)methyl)-21-oxo-3,6,9,12,15,18,25-heptaoxa-22-azaoctacosan-28-oate
IUPAC Name	tert-butyl 3-[2-[3-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]-2-[[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]methyl]propoxy]propanoate
SMILES	O=C(OC(C)(C)C)CCOCC(COCCC(OC(C)(C)C)=O)(NC(CCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O)COCCC(OC(C)(C)C)=O
InChI	InChI=1S/C40H74N4O16/c1-37(2,3)58-34(46)11-16-55-30-40(31-56-17-12-35(47)59-38(4,5)6,32-57-18-13-36(48)60-39(7,8)9)43-33(45)10-15-49-20-22-51-24-26-53-28-29-54-27-25-52-23-21-50-19-14-42-44-41/h10-32H2,1-9H3,(H,43,45)
InChIKey	BHSDUCHVJCFXOS-UHFFFAOYSA-N
Purity	≥95%
Storage	Store at 2-8°C

Azido-PEG6-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a multifunctional compound used in various chemical and biological applications. Here are some key applications of Azido-PEG6-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane:

Bioconjugation: Azido-PEG6-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is commonly used in bioconjugation techniques to link biomolecules such as proteins, DNA, and antibodies. The azido group enables bioorthogonal click chemistry reactions, allowing for highly specific and efficient coupling. This method is essential for creating novel biomolecular assemblies and diagnostic probes.

Drug Delivery Systems: This compound can be utilized to develop advanced drug delivery systems by serving as a linker between therapeutic agents and targeting moieties. The PEGylation improves the solubility and biocompatibility of drug conjugates, enhancing their stability and circulation time in the body. This results in more effective targeting of diseased tissues and reduces systemic side effects.

Surface Functionalization: In material science, Azido-PEG6-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is used to functionalize surfaces of nanoparticles, polymers, and other materials. The azido group allows for stable attachment to a variety of substrates, facilitating the creation of functionalized surfaces with tailored properties. This is particularly useful in developing biosensors, biochips, and other bioengineering applications.

Proteomics and Genomics: This compound is useful in proteomics and genomics research for labeling and detecting biomolecules. By conjugating with azido-tagged probes, researchers can selectively tag and visualize specific proteins, nucleic acids, or cellular components. This facilitates the study of complex biological systems and the identification of novel biomarkers.

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