Azido-PEG6-alcohol

Name: Azido-PEG6-alcohol
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 86770-69-6

Cat No.: BPG-1928

Purity: >98.0%

4.5

Azido-PEG6-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Azido-PEG6-alcohol is also a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Category	Small-molecule Heterobifunctional PEG
Molecular Formula	C12H25N3O6
Molecular Weight	307.34
Appearance	Solid
Shipping	Room temperature
Storage	Store at -20 °C, keep in dry and avoid sunlight.

Structure of 86770-69-6

Ordering Information

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Synonyms	N3-PEG6-OH; 17-azido-3,6,9,12,15-pentaoxaheptadecan-1-ol
IUPACName	2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
CanonicalSMILES	C(COCCOCCOCCOCCOCCO)N=[N+]=[N-]
InChI	InChI=1S/C12H25N3O6/c13-15-14-1-3-17-5-7-19-9-11-21-12-10-20-8-6-18-4-2-16/h16H,1-12H2
InChIKey	DPRULTZUGLDCPZ-UHFFFAOYSA-N
Purity	>98.0%
Solubility	10 mm in DMSO
ShelfLife	0-4°C for short term (days to weeks), or -20°C for long term (months).

PEGType	Discrete PEG Linker
PEGArchitecture	Linear
Functionality	Heterobifunctional

ReactiveToward	Terminal Alkynes; Strained Alkynes (DBCO/BCN); Activated Carboxyls / Isocyanates
ReactionChemistry	CuAAC Click Chemistry; SPAAC Click Chemistry; Esterification / Carbamate Formation
BiomoleculeCompatibility	Click-Handle-Modified Proteins / Peptides; Click-Handle-Modified Antibodies; Click-Handle-Modified Oligonucleotides; Small Molecules / Probes
ResearchUse	Copper-Free Azide–Cyclooctyne Ligation; Copper-Catalyzed Azide–Alkyne Ligation; Ester / Carbamate Formation