Azido-PEG5-(CH2)3-methyl ester

Name: Azido-PEG5-(CH2)3-methyl ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	Azido-PEGn-(CH2)3-methyl ester
Catalog NO.	BPG-0016
Product Name	Azido-PEG5-(CH2)3-methyl ester
Molecular Formula	C15H29N3O7
Molecular Weight	363.40

Azido-PEG5-(CH2)3-methyl ester @(data.CAS != null ? $"| CAS " : "") - BOC Sciences

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Description	Azido-PEG5-(CH2)3-methyl ester is a crosslinker containing an azide group with PEG5 units. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms	methyl 1-azido-3,6,9,12,15-pentaoxanonadecan-19-oate
IUPAC Name	methyl 4-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]butanoate
SMILES	O=C(OC)CCCOCCOCCOCCOCCOCCN=[N+]=[N-]
InChI	InChI=1S/C15H29N3O7/c1-20-15(19)3-2-5-21-7-9-23-11-13-25-14-12-24-10-8-22-6-4-17-18-16/h2-14H2,1H3
InChIKey	RDYAUOXBKNKYIV-UHFFFAOYSA-N
Purity	≥95%
Storage	Store at 2-8°C

Azido-PEG5-(CH2)3-methyl ester is a versatile compound widely applied in the fields of chemical biology and material science. Here are four key applications presented with a high degree of perplexity and burstiness:

Bioconjugation: Acting as a crucial player in bioconjugation reactions, Azido-PEG5-(CH2)3-methyl ester serves to bridge biomolecules like proteins, peptides, and nucleic acids through the intricate dance of click chemistry. By facilitating the incorporation of azido groups onto biomolecules, this compound sets the stage for their subsequent interaction with alkynes. This method, a cornerstone in the realm of targeted drug delivery systems and diagnostic tools, embodies precision and innovation in molecular engineering.

Surface Modification: A catalyst for transformation, this compound is harnessed to revolutionize surfaces by introducing azido groups primed for click reactions with alkyne-functionalized molecules. This advanced technique allows for the meticulous and selective customization of diverse surfaces, from nanoparticles to biomaterial coatings. The tailored surfaces, adapted for applications spanning biosensing, biocompatibility, and anti-fouling properties, epitomize the fusion of science and art in material design.

Drug Delivery: A linchpin in the orchestration of cutting-edge drug delivery systems, Azido-PEG5-(CH2)3-methyl ester plays a pivotal role in enhancing therapeutic efficacy. By linking therapeutic agents with PEG-modified carriers through azide-alkyne cycloaddition, researchers orchestrate the enhancement of drug solubility, stability, and bioavailability. This innovation culminates in the optimization of drug delivery efficiency, enabling precise targeting of pharmaceutical payloads to specific cells or tissues with unparalleled precision.

Molecular Probes and Imaging: A beacon in the realm of molecular probes and imaging, this compound emboldens scientists in their quest to unravel the mysteries of biological processes. Its affinity for alkyne groups empowers the attachment of fluorescent labels, radiolabels, and other imaging agents to biomolecules, facilitating the visualization and tracking of intricate biological pathways.

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