Azido-PEG4-hydrazide
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-1924 |
| Product Name | Azido-PEG4-hydrazide |
| CAS | 2170240-96-5 |
| Molecular Formula | C₁₁H₂₃N₅O₅ |
| Molecular Weight | 305.33 |
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| Description | Azido-PEG4-hydrazide is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG4-hydrazide can be used in the synthesis of a series of PROTACs. |
| Synonyms | Azido-PEG4-hydrazide HCl Salt;N3-PEG4-Hydrazide |
| IUPAC Name | 3-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]propanehydrazide |
| Canonical SMILES | C(COCCOCCOCCOCCN=[N+]=[N-])C(=O)NN |
| InChI | InChI=1S/C11H23N5O5/c12-15-11(17)1-3-18-5-7-20-9-10-21-8-6-19-4-2-14-16-13/h1-10,12H2,(H,15,17) |
| InChIKey | BUAWGAVOHIVJRC-UHFFFAOYSA-N |
| Purity | >95% |
| Solubility | In DMSO: 100 mg/mL (327.51 mM; Need ultrasonic) |
| Storage | -20°C, protect from light; In solvent, -80°C, 6 months; -20°C, 1 month (protect from light) |
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Resources
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Technical Information
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- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
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- PEG for Chemical Synthesis
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- Polyethylene Glycol (PEG) Modifier Selection Guide
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Industry News
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- Classification of Lipid-Based Vaccine Adjuvants
- FDA approved PEGylated Products
- FDA-Approved Antibody-Drug Conjugates up to 2024
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- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
- Lipid-Drug Conjugates (LDCs) for Nanoparticle Drug Delivery
- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
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