Azido-PEG3-NHS ester

Name: Azido-PEG3-NHS ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 1245718-89-1

Cat No.: BPG-3556

Purity: ≥98%

4.5

Azido-PEG3-NHS ester is a PEG-containing bioorthogonal conjugation building block that provides an azide handle for modular click-chemistry workflows. The molecule can be used to introduce a click-reactive group onto an antibody, peptide, linker intermediate, or payload-containing component, depending on the chemistry of its second terminal functionality. Its additional reactive group is nhs/succinimidyl ester (amine-reactive) for antibody lysines/primary amines. The structure includes peg3 spacer to provide hydrophilic spacing. Conjugation can be performed using spaac with dbco/bcn-functionalized partner or cuaac with terminal alkyne partner, depending the complementary handle. The sequence and orientation of the coupling steps should be selected according to the functional groups carried by the two conjugation partners.

Category	Azido-PEGn-NHS ester
Molecular Formula	C13H20N4O7
Molecular Weight	344.32
Appearance	Pale Yellow or Colorless Oily Matter
Shipping	Room temperature
Storage	Store at 2-8°C

Structure of 1245718-89-1

Ordering Information

*For research and manufacturing use only. We do not sell to patients.

Fast-Track Access to Precise Molecular Weight Products

Professional Solutions for Molecular Research

cGMP Capacity

cGMP-compliant manufacturing options
Comprehensive QC testing with COA, MSD
From mg and g to kg-scale production
In-stock supply in the US and Europe
Global supply & fast worldwide delivery
One-stop PEGylation services
Custom PEG reagents synthesis
Click chemistry reagents
Bioconjugation & drug delivery
Trusted by 100+ research institutions

Popular Publications Citing BOC Sciences Products

Specification

Synonyms	Azido-PEG3-CH2CO2-NHS; N3-PEG3-C2-NHS ester; N3-PEG3-CH2CH2COONHS Ester; 1-[(3-{2-[2-(2-Azidoethoxy)ethoxy]ethoxy}propanoyl)oxy]-2,5-pyrrolidinedione; 2,5-Pyrrolidinedione, 1-[3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-1-oxopropoxy]-; N3-PEG3-SPA; Propanoic acid, 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester
IUPACName	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]propanoate
CanonicalSMILES	C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCN=[N+]=[N-]
InChI	InChI=1S/C13H20N4O7/c14-16-15-4-6-22-8-10-23-9-7-21-5-3-13(20)24-17-11(18)1-2-12(17)19/h1-10H2
InChIKey	BNLXVOZUEBSSRI-UHFFFAOYSA-N
Purity	≥98%
Solubility	Soluble in DCM, DMF, DMSO, Water
RelatedCAS	1108750-59-9 (polymer)
ShelfLife	≥12 months if stored properly