Azido-PEG2-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane

Name: Azido-PEG2-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	Azido-PEGn-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane
Catalog NO.	BPG-0886
Product Name	Azido-PEG2-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane
Molecular Formula	C32H58N4O12
Molecular Weight	690.83

Azido-PEG2-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane @(data.CAS != null ? $"| CAS " : "") - BOC Sciences

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Description	Azido-PEG2-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a branched PEG derivative with a terminal azide group and three t-butyl esters. The azide group enables PEGylation via Click Chemistry. The t-butyl protected carboxyl groups can be deprotected under mild acidic conditions.
Synonyms	tert-butyl 1-azido-11,11-bis((3-(tert-butoxy)-3-oxopropoxy)methyl)-9-oxo-3,6,13-trioxa-10-azahexadecan-16-oate
IUPAC Name	tert-butyl 3-[2-[3-[2-(2-azidoethoxy)ethoxy]propanoylamino]-3-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]-2-[[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]methyl]propoxy]propanoate
SMILES	O=C(OC(C)(C)C)CCOCC(COCCC(OC(C)(C)C)=O)(NC(CCOCCOCCN=[N+]=[N-])=O)COCCC(OC(C)(C)C)=O
InChI	InChI=1S/C32H58N4O12/c1-29(2,3)46-26(38)11-16-43-22-32(23-44-17-12-27(39)47-30(4,5)6,24-45-18-13-28(40)48-31(7,8)9)35-25(37)10-15-41-20-21-42-19-14-34-36-33/h10-24H2,1-9H3,(H,35,37)
InChIKey	QOQVNBQHQSFLPG-UHFFFAOYSA-N
Purity	≥95%
Storage	Store at 2-8°C

Azido-PEG2-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane, a versatile reagent utilized in a myriad of chemical and biological applications, is showcased through four key applications presented with heightened perplexity and burstiness:

Bioconjugation: Emerging as a pivotal player in the realm of bioconjugation, Azido-PEG2-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane serves as a crucial linker for connecting biomolecules, such as peptides, proteins, or antibodies, to diverse substrates or surfaces. The azide unit, conducive to selective targeting in click chemistry approaches, enables precise and efficient attachment at specific sites. This intricate process lays the groundwork for crafting bioconjugates essential in diagnostics, therapeutics, and the burgeoning field of biomolecular engineering.

Drug Delivery: Spearheading advancements in drug delivery systems, the adaptable Azido-PEG2-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane takes the lead. Here, the polyethylene glycol (PEG) component imparts water solubility and biocompatibility, while the azide functionality facilitates seamless conjugation of therapeutic payloads. This dynamic synergy empowers the development of drug conjugates poised to elevate the stability, solubility, and targeted delivery of pharmaceutical agents, ultimately enhancing therapeutic efficacy to unprecedented heights.

Surface Functionalization: At the forefront of surface functionalization technologies stands Azido-PEG2-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane, a catalyst for imbuing various surfaces with tailored functionalities, spanning from nanoparticles to polymers and medical devices. By grafting this compound onto surfaces, researchers introduce modifiable functional groups that not only enable subsequent chemical alterations but also enhance biocompatibility. This transformative approach finds significant utility in crafting biosensors, imaging agents, and cutting-edge implantable medical devices, propelling innovation in biomedical engineering.

Bioorthogonal Chemistry: The azide-laden Azido-PEG2-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane emerges as a linchpin in bioorthogonal chemistry, a suite of reactions that occur within living organisms without disrupting native biochemical processes. This compound finds its niche in live-cell imaging, enabling the tagging and visualization of specific biomolecules with exceptional precision. Moreover, its utility extends to investigating cellular dynamics and interplay within their native biological milieu, shedding light on complex biological interactions and processes.

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