Azide-PEG5-Tos
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-2118 |
| Product Name | Azide-PEG5-Tos |
| CAS | 236754-49-7 |
| Molecular Formula | C17H27N3O7S |
| Molecular Weight | 417.48 |
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| Description | Azide-PEG5-Tos is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Synonyms | 14-Azido-3,6,9,12-tetraoxatetradecyl 4-methylbenzenesulfonate |
| IUPAC Name | 2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate |
| Canonical SMILES | CC1=CC=C(C=C1)S(=O)(=O)OCCOCCOCCOCCOCCN=[N+]=[N-] |
| InChI | InChI=1S/C17H27N3O7S/c1-16-2-4-17(5-3-16)28(21,22)27-15-14-26-13-12-25-11-10-24-9-8-23-7-6-19-20-18/h2-5H,6-15H2,1H3 |
| InChIKey | RCRFPWKHJGMATE-UHFFFAOYSA-N |
| Purity | >98.0% |
| Solubility | 10 mm in DMSO |
| Appearance | Solid Power |
| Shelf Life | ≥ 2 years |
| Storage | Store at -20 °C, keep in dry and avoid sunlight. |
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Technical Information
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Industry News
- Applications of PEG-DSPE: Drug Carriers and Drug Delivery
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- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
- What are Monodispersed and Polydispersed PEGs?
- What are PEG Lipids?
- What are Phospholipids?
- What is Click Chemistry?
- What is Hydrogel?
- What is Methoxy Polyethylene Glycol (mPEG)?
- What is Nanogels and Its Applications?
- What is the Formulation of Lipid Nanoparticles (LNPs)?
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PEGylation of Peptides
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Reduce the Immunogenicity of Peptide/Protein Drugs
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