Aminooxy-PEG11-Aminooxy

Name: Aminooxy-PEG11-Aminooxy
Brand: BOC Sciences
Rating: 5 (1 reviews)

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Category	Aminooxy-PEGn-Aminooxy
Catalog NO.	BPG-0786
Product Name	Aminooxy-PEG11-Aminooxy
Molecular Formula	C24H52N2O13
Molecular Weight	576.68

Aminooxy-PEG11-Aminooxy @(data.CAS != null ? $"| CAS " : "") - BOC Sciences

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Description	Aminooxy-PEG11-Aminooxy is a PEG derivative containing two aminooxy groups that can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
Synonyms	Bis-aminooxy-PEG11; O,O'-(3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontane-1,35-diyl)bis(hydroxylamine)
IUPAC Name	O-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminooxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]hydroxylamine
SMILES	NOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCON
InChI	InChI=1S/C24H52N2O13/c25-38-23-21-36-19-17-34-15-13-32-11-9-30-7-5-28-3-1-27-2-4-29-6-8-31-10-12-33-14-16-35-18-20-37-22-24-39-26/h1-26H2
InChIKey	MSSSFHRGVMZDMF-UHFFFAOYSA-N
Purity	≥95%
Appearance	Pale Yellow or Colorless Oily Matter
Storage	Store at 2-8°C

Aminooxy-PEG11-Aminooxy, a versatile bifunctional crosslinker, finds diverse utility in biochemical and therapeutic realms. Here are four key applications of Aminooxy-PEG11-Aminooxy presented with high perplexity and burstiness:

Drug Delivery: Harnessing the power of Aminooxy-PEG11-Aminooxy, researchers can amplify the delivery of therapeutic agents to precise anatomical sites within the body. Its bifunctional character enables seamless conjugation of drugs with carriers like nanoparticles or antibodies. This targeted delivery strategy not only heightens treatment efficacy but also diminishes adverse effects.

Bioconjugation: Boasting exceptional efficacy in bioconjugation, this compound adeptly links biomolecules such as proteins, peptides, or nucleic acids for a myriad of research and therapeutic objectives. The PEG11 spacer plays a pivotal role in upholding the bioactivity of the conjugated molecules by furnishing stabilization and mitigating steric hindrance. This capability is indispensable for crafting biocompatible conjugates essential in diagnostics and therapeutic interventions.

Surface Functionalization: Aminooxy-PEG11-Aminooxy emerges as a quintessential tool in surface functionalization endeavors, be it in biosensors or medical implants. By instating a reactive layer on these surfaces, researchers can judiciously immobilize biomolecules in a controlled fashion, thereby enhancing device functionality and biocompatibility. This application stands at the forefront of cutting-edge diagnostic technologies and biointerface engineering.

Protein Modification: In the realm of protein engineering and therapeutic protein development, Aminooxy-PEG11-Aminooxy shines as a catalyst for site-specific protein modification. By honing in on specific functional groups, it enables precise alterations without compromising protein functionality. This surgical precision underpins the creation of highly selective biologic drugs and exploration of intricate protein-protein interactions.

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