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Acs-PEG4-propargyl

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Category AcS-PEGn-propargyl
Catalog NO. BPG-1119
Product Name Acs-PEG4-propargyl
CAS 1422540-88-2
Molecular Formula C13H22O5S
Molecular Weight 290.37
Acs-PEG4-propargyl
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Product Information

Description Acs-PEG4-propargyl is a PEG linker containing a sulfur acetyl group and a propargyl moiety. The sulfur acetyl group can be deprotected to produce a thiol compound. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG linker increases the water solubility of the compounds in the aqueous media.
Synonyms S-acetyl-PEG4-Propargyl; Acetylthio-PEG4-Alkyne; S-acetyl-PEG4-alkyne; S-(3,6,9,12-Tetraoxapentadec-14-yn-1-yl) ethanethioate; Ethanethioic acid, S-3,6,9,12-tetraoxapentadec-14-yn-1-yl ester
IUPAC Name S-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethyl] ethanethioate
Canonical SMILES CC(=O)SCCOCCOCCOCCOCC#C
InChI InChI=1S/C13H22O5S/c1-3-4-15-5-6-16-7-8-17-9-10-18-11-12-19-13(2)14/h1H,4-12H2,2H3
InChIKey IOVXBDYSVBLUMS-UHFFFAOYSA-N
Boiling Point 375.6±37.0°C at 760 mmHg
Purity ≥95%
Density 1.1±0.1 g/cm3
Solubility Soluble in DCM, DMF, DMSO
Appearance Yellow to Amber to Dark Red Clear Liquid
Storage Store at 2-8°C

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PEGylation of Peptides and Proteins

PEGylation of Peptides
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