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Acid-PEG4-NHS ester
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| Category | Small-molecule NHS ester PEG |
| Catalog NO. | BPG-4805 |
| Product Name | Acid-PEG4-NHS ester |
| CAS | 2639395-41-6 |
| Molecular Formula | C16H25NO10 |
| Molecular Weight | 391.37 |
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| Description | Acid-PEG4-NHS ester is a PEG linker that can be used to introduce PEGylation to various biomolecules, such as antibodies, enzymes, and peptides, improving their solubility, stability, and pharmacokinetics. |
| Synonyms | 4,7,10,13-Tetraoxahexadecanedioic acid, 1-(2,5-dioxo-1-pyrrolidinyl) ester |
| IUPAC Name | 3-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]propanoic acid |
| Canonical SMILES | C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCC(=O)O |
| InChI | InChI=1S/C16H25NO10/c18-13-1-2-14(19)17(13)27-16(22)4-6-24-8-10-26-12-11-25-9-7-23-5-3-15(20)21/h1-12H2,(H,20,21) |
| InChIKey | UZALGPVEUZNYBM-UHFFFAOYSA-N |
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Resources
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Technical Information
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- How to Perform Polyethylene Glycol (PEG) Modification?
- Hydrophobic Interaction Chromatography (HIC) Technique
- Introduction of Polyethylene Glycol (PEG)
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- Polyethylene Glycol (PEG) Modifier Selection Guide
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Industry News
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- FDA-Approved Antibody-Drug Conjugates up to 2024
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- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
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- Liposome in Drug Delivery
- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
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- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
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BOC Sciences supplies a unique variety of PEG derivatives and functional PEG polymers. Our products offer the most diverse collection of reactivity, ready-to-use functionality, and molecular weight options that you will not find anywhere else.
PEGylation of Peptides
and Proteins
Reduce the Immunogenicity of Peptide/Protein Drugs
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APPLICATIONS
PEG linkers For Drug
Improved Circulation Half-Life
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