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Acid-PEG4-NHS ester

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Category	Acid-PEGn-NHS ester
Catalog NO.	BPG-1036
Product Name	Acid-PEG4-NHS ester
Molecular Formula	C16H25NO10
Molecular Weight	391.37

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Description	Acid-PEG4-NHS ester is a PEG linker containing a carboxylic acid and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Synonyms	Acid-C2-PEG4-NHS ester; COOH-PEG4-SPA; COOH-PEG4-NHS; 16-((2,5-dioxopyrrolidin-1-yl)oxy)-16-oxo-4,7,10,13-tetraoxahexadecanoic acid
IUPAC Name	3-[2-[2-[2-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES	C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCC(=O)O
InChI	InChI=1S/C16H25NO10/c18-13-1-2-14(19)17(13)27-16(22)4-6-24-8-10-26-12-11-25-9-7-23-5-3-15(20)21/h1-12H2,(H,20,21)
InChIKey	UZALGPVEUZNYBM-UHFFFAOYSA-N
Purity	≥95%
Related CAS	1643594-31-3 (polymer)
Appearance	Light Yellow or White Solid
Storage	Store at 2-8°C

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