3,4-Dibromo-Mal-PEG8-Azide

Name: 3,4-Dibromo-Mal-PEG8-Azide
Brand: BOC Sciences
Rating: 5 (1 reviews)

Cat No.: BPG-4369

Purity: 0.98

4.5

3,4-Dibromo-Mal-PEG8-Azide is a PEG linker featuring a dibromo-maleimide linked to an azide group. The unsaturated dibromo motif is a covalent ligand for thiol groups, and may be used to label cysteine residues in proteins. The azide is a click chemistry handle which may be used to link with terminal alkynes or strained cyclooctynes like DBCO or BCN. The presence of two leaving groups on this molecule allows this linker to bind two thiols at a time.

Category	Small-molecule Maleimide PEG
Molecular Formula	C22H36Br2N4O10
Molecular Weight	676.4
Shipping	Ambient temperature
Storage	-20°C

Structure of 3,4-Dibromo-Mal-PEG8-Azide

Ordering Information

*For research and manufacturing use only. We do not sell to patients.

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Purity

0.98

PEGType	Discrete PEG Linker
PEGArchitecture	Linear
Functionality	Heterobifunctional

ReactiveToward	Thiols; Terminal Alkynes; Strained Alkynes (DBCO/BCN)
ReactionChemistry	Maleimide-Thiol Conjugation; CuAAC Click Chemistry; SPAAC Click Chemistry
BiomoleculeCompatibility	Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides; Click-Handle-Modified Proteins / Peptides; Click-Handle-Modified Antibodies; Click-Handle-Modified Oligonucleotides; Small Molecules / Probes
ResearchUse	Copper-Free Azide–Cyclooctyne Ligation; Copper-Catalyzed Azide–Alkyne Ligation; Thiol-Selective Biomolecule Conjugation