2,3,4-(PEG4-Azide)-1-(PEG4-Amine)methane

Name: 2,3,4-(PEG4-Azide)-1-(PEG4-Amine)methane
Brand: BOC Sciences
Rating: 5 (1 reviews)

Cat No.: BPG-4005

Purity: 0.95

4.5

2,3,4-(PEG4-Azide)-1-(PEG4-Amine)methane is a four-armed PEG reagent that combines three azide groups with a primary amine. Azides are frequently used in click reactions with terminal alkynes, DBCO and BCN moieties to form stable triazole linkages with the target molecule. Primary amines are useful scaffolds for easily building complexity such as in making amides, building heterocycles, and performing SNAr reactions on electron-deficient aromatic compounds. PEG linkers increase a molecule's water solubility and their use impacts a compound's ADME properties in vivo.

Category	Azide Branched PEG
Molecular Formula	C37H74N10O16
Molecular Weight	915.1
Shipping	Ambient temperature
Storage	-20°C

Structure of 2,3,4-(PEG4-Azide)-1-(PEG4-Amine)methane

Ordering Information

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Purity

0.95

PEGType	Discrete PEG Linker
PEGArchitecture	Linear
Functionality	Heterobifunctional

ReactiveToward	Terminal Alkynes; Strained Alkynes (DBCO/BCN); Activated Carboxyls / Activated Esters
ReactionChemistry	CuAAC Click Chemistry; SPAAC Click Chemistry; Amide Coupling
BiomoleculeCompatibility	Click-Handle-Modified Proteins / Peptides; Click-Handle-Modified Antibodies; Click-Handle-Modified Oligonucleotides; Small Molecules / Probes; Proteins / Antibodies; Peptides; Carboxyl-Modified Oligonucleotides
ResearchUse	Copper-Free Azide–Cyclooctyne Ligation; Copper-Catalyzed Azide–Alkyne Ligation; Amide Bond Formation