| Category | Small-molecule Heterobifunctional PEG |
| Molecular Formula | C₁₀H₂₂ClNO₂ |
| Molecular Weight | 223.74 |
| Appearance | Transparent Liquid |
| Shipping | Room temperature in continental US; may vary elsewhere. |
| Storage | -20°C, protect from light, stored under nitrogen; In solvent, -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
2-(2-(6-chlorohexyloxy)ethoxy)ethanamine
4.5
NH2-PEG2-C6-Cl is a polyethylene glycol (PEG)-based PROTAC linker. NH2-PEG2-C6-Cl can be used in the synthesis of a series of PROTACs.
Structure of 744203-60-9
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- Specification
- Key Product Attributes
- Reaction & Conjugation Properties
| Synonyms | 2-(2-((6-Chlorohexyl)oxy)ethoxy)ethanamine; 2-[2-(6-Chloro-hexyloxy)-ethoxy]-ethylamine |
| IUPACName | 2-[2-(6-chlorohexoxy)ethoxy]ethanamine |
| CanonicalSMILES | C(CCCCl)CCOCCOCCN |
| InChI | InChI=1S/C10H22ClNO2/c11-5-3-1-2-4-7-13-9-10-14-8-6-12/h1-10,12H2 |
| InChIKey | ABAUJBZQEHFSKW-UHFFFAOYSA-N |
| BoilingPoint | 313.1±27.0 °C at 760 mmHg |
| Purity | >95% |
| Density | 1.0±0.1 g/cm3 |
| Solubility | In DMSO: 100 mg/mL (446.95 mM; Need ultrasonic) |
| PEGType | PEG / Oligoethylene Glycol Building Block |
| PEGArchitecture | Linear |
| Functionality | Heterobifunctional |
| ReactiveToward | Nucleophiles (Amines / Thiols); Activated Carboxyls / Activated Esters |
| ReactionChemistry | Nucleophilic Substitution; Amide Coupling |
| BiomoleculeCompatibility | Amine- or Thiol-Functionalized Biomolecules; Proteins / Antibodies; Peptides; Carboxyl-Modified Oligonucleotides |
| ResearchUse | Amide Bond Formation; Nucleophilic Linker Substitution |
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