| Category | Small-molecule Heterobifunctional PEG |
| Molecular Formula | C₁₂H₂₄ClN₃O₃ |
| Molecular Weight | 293.79 |
| Appearance | Transparent Liquid |
| Shipping | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
1-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)-6-chlorohexane
Azido-PEG3-C6-Cl is a polyethylene glycol (PEG)-based PROTAC linker. Azido-PEG3-C6-Cl can be used in the synthesis of a series of PROTACs.
Structure of 1625717-44-3
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- Specification
- Key Product Attributes
- Reaction & Conjugation Properties
| Synonyms | Azido-PEG3-C6-Cl |
| IUPACName | 1-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-6-chlorohexane |
| CanonicalSMILES | C(CCCCl)CCOCCOCCOCCN=[N+]=[N-] |
| InChI | InChI=1S/C12H24ClN3O3/c13-5-3-1-2-4-7-17-9-11-19-12-10-18-8-6-15-16-14/h1-12H2 |
| InChIKey | LRKXYBSEUKVYAX-UHFFFAOYSA-N |
| Purity | >95% |
| PEGType | PEG / Oligoethylene Glycol Building Block |
| PEGArchitecture | Linear |
| Functionality | Monofunctional (Reactive) |
| ReactiveToward | Terminal Alkynes; Strained Alkynes (DBCO/BCN); Nucleophiles (Amines / Thiols) |
| ReactionChemistry | CuAAC Click Chemistry; SPAAC Click Chemistry; Nucleophilic Substitution |
| BiomoleculeCompatibility | Click-Handle-Modified Proteins / Peptides; Click-Handle-Modified Antibodies; Click-Handle-Modified Oligonucleotides; Small Molecules / Probes; Amine- or Thiol-Functionalized Biomolecules |
| ResearchUse | Copper-Free Azide–Cyclooctyne Ligation; Copper-Catalyzed Azide–Alkyne Ligation; Nucleophilic Linker Substitution |
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