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Tr-PEG8-OH

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Category Tr-PEGn-OH
Catalog NO. BPG-3345
Product Name Tr-PEG8-OH
CAS 1144113-16-5
Molecular Formula C35H48O9
Molecular Weight 612.74
Tr-PEG8-OH
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Product Information

Description Tr-PEG8-OH is a PROTAC linker (belonging to the PEG class) that can be used to synthesize PROTAC molecules. Tr-PEG8-OH is also a non-cleavable 8-unit PEG ADC linker that is used in the synthesis of antibody-conjugated drugs (ADCs).
Synonyms Tr-PEG9; Tr-PEG8-alcohol; 2,5,8,11,14,17,20,23-Octaoxapentacosan-25-ol, 1,1,1-triphenyl-; 23-(Trityloxy)-3,6,9,12,15,18,21-heptaoxatricosane-1-ol; 1,1,1-Triphenyl-2,5,8,11,14,17,20,23-octaoxapentacosan-25-ol
IUPAC Name 2-[2-[2-[2-[2-[2-[2-(2-trityloxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Canonical SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCOCCOCCOCCOCCOCCOCCOCCO
InChI InChI=1S/C35H48O9/c36-16-17-37-18-19-38-20-21-39-22-23-40-24-25-41-26-27-42-28-29-43-30-31-44-35(32-10-4-1-5-11-32,33-12-6-2-7-13-33)34-14-8-3-9-15-34/h1-15,36H,16-31H2
InChIKey QMAWPOYSSQJMMG-UHFFFAOYSA-N
Boiling Point 692.1±50.0°C at 760 mmHg
Purity ≥95%
Density 1.1±0.1 g/cm3
Solubility Soluble in DMSO
Shelf Life 0-4 °C for short term (days to weeks), or -20 °C for long term (months).
Storage Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

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PEGylation of Peptides and Proteins

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