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Tr-PEG4-OH

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Category Tr-PEGn-OH
Catalog NO. BPG-3349
Product Name Tr-PEG4-OH
CAS 125274-16-0
Molecular Formula C27H32O5
Molecular Weight 436.54
Tr-PEG4-OH
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Product Information

Description Tr-PEG4-OH is a PROTAC linker (belonging to the PEG class) that can be used to synthesize PROTAC molecules. Tr-PEG4-OH is also a non-cleavable 4-unit PEG ADC linker that is used in the synthesis of antibody-conjugated drugs (ADCs).
Synonyms Tr-PEG5; Tr-PEG4-alcohol; 2,5,8,11-Tetraoxatridecan-13-ol, 1,1,1-triphenyl-; 3,6,9,12-Tetraoxatridecan-1-ol, 13,13,13-triphenyl-; 11-(Trityloxy)-3,6,9-trioxaundecane-1-ol; 11-Triphenylmethyloxy-3,6,9-trioxaundecan-1-ol; 1,1,1-Triphenyl-2,5,8,11-tetraoxatridecan-13-ol
IUPAC Name 2-[2-[2-(2-trityloxyethoxy)ethoxy]ethoxy]ethanol
Canonical SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCOCCOCCOCCO
InChI InChI=1S/C27H32O5/c28-16-17-29-18-19-30-20-21-31-22-23-32-27(24-10-4-1-5-11-24,25-12-6-2-7-13-25)26-14-8-3-9-15-26/h1-15,28H,16-23H2
InChIKey NVNUQXMSFVIKJG-UHFFFAOYSA-N
Boiling Point 559.6±45.0°C at 760 mmHg
Purity ≥95%
Density 1.1±0.1 g/cm3
Solubility Soluble in DMSO
Appearance Light Yellow Oily Matter
Storage Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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