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Tr-PEG2-OH

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Category Tr-PEGn-OH
Catalog NO. BPG-3355
Product Name Tr-PEG2-OH
CAS 105589-77-3
Molecular Formula C23H24O3
Molecular Weight 348.44
Tr-PEG2-OH
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Product Information

Description Tr-PEG2-OH is a PROTAC linker (belonging to the PEG class) that can be used to synthesize PROTAC molecules. Tr-PEG2-OH is also a non-cleavable 2-unit PEG ADC linker that is used in the synthesis of antibody-conjugated drugs (ADCs).
Synonyms Tr-PEG3; Tr-PEG2-alcohol; Ethanol, 2-[2-(triphenylmethoxy)ethoxy]-; 2-(2-(trityloxy)ethoxy)ethan-1-ol; 2-[2-(Triphenylmethoxy)ethoxy]ethan-1-ol; Ethanol, 2-[2-(triphenylmethoxy)ethoxy]-
IUPAC Name 2-(2-trityloxyethoxy)ethanol
Canonical SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCOCCO
InChI InChI=1S/C23H24O3/c24-16-17-25-18-19-26-23(20-10-4-1-5-11-20,21-12-6-2-7-13-21)22-14-8-3-9-15-22/h1-15,24H,16-19H2
InChIKey RPCPDUOXPSQJHC-UHFFFAOYSA-N
Boiling Point 481.9±40.0°C (Predicted)
Purity ≥95%
Density 1.127±0.06 g/cm3 (Predicted)
Solubility Soluble in DMSO
Appearance Solid
Shelf Life 0-4°C for short term (days to weeks), or -20°C for long term (months).
Storage Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
LogP 4.00400

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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