THP-PEG6-alcohol
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| Category | Small-molecule Heterobifunctional PEG |
| Catalog NO. | BPG-2037 |
| Product Name | THP-PEG6-alcohol |
| CAS | 42607-87-4 |
| Molecular Formula | C17H34O8 |
| Molecular Weight | 366.45 |
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| Description | THP-PEG6-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. THP-PEG6-OH is also a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Synonyms | OH-PEG6-THP; HO-PEG6-THP; THP-PEG7; THP-PEG6-OH; 3,6,9,12,15-Pentaoxaheptadecan-1-ol, 17-[(tetrahydro-2H-pyran-2-yl)oxy]-; 17-((Tetrahydro-2H-pyran-2-yl)oxy)-3,6,9,12,15-pentaoxaheptadecan-1-ol |
| IUPAC Name | 2-[2-[2-[2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
| Canonical SMILES | C1CCOC(C1)OCCOCCOCCOCCOCCOCCO |
| InChI | InChI=1S/C17H34O8/c18-4-6-19-7-8-20-9-10-21-11-12-22-13-14-23-15-16-25-17-3-1-2-5-24-17/h17-18H,1-16H2 |
| InChIKey | ABJWCLPYMPRGRB-UHFFFAOYSA-N |
| Boiling Point | 469.0±45.0 °C at 760 mmHg |
| Purity | ≥95% |
| Density | 1.10±0.1 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO (10 mm) |
| Appearance | Solid |
| Shelf Life | -20℃ 3 years powder; -80℃ 2 years in solvent |
| Storage | Store at 2-8°C |
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Industry News
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- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
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- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- What are Biotinylation and Biotinylated PEG?
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
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PEGylation of Peptides
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