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THP-PEG2-alcohol

CAS No. CAS No.: 2163-11-3
Cat No. Cat No.: BPG-1734
Purity Purity: ≥95%
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HO-PEG2-THP is a polyethylene glycol (PEG)-based PROTAC linker that can be used in the synthesis of a series of PROTACs.

Category HO-PEGn-THP
Molecular Formula C9H18O4
Molecular Weight 190.24
Appearance Clear Colorless Oily Matter
Shipping Room temperature in continental US; may vary elsewhere.
Storage Store at 2-8°C
THP-PEG2-alcohol

Structure of 2163-11-3

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  • Specification
  • Key Product Attributes
  • Reaction & Conjugation Properties
Synonyms OH-PEG2-THP; THP-PEG3; HO-PEG2-THP; THP-PEG2-OH; Tetrahydropyranyldiethyleneglycol; 2-[2-(Tetrahydropyranyloxy)ethoxy]ethanol; Diethylene Glycol Mono(tetrahydro-2-pyranyl) Ether; Ethanol, 2-[2-[(tetrahydro-2H-pyran-2-yl)oxy]ethoxy]-; 2-(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethan-1-ol; 2-[2-(Tetrahydro-2H-pyran-2-yloxy)ethoxy]ethanol; 2-[2-(oxan-2-yloxy)ethoxy]ethan-1-ol
IUPACName 2-[2-(oxan-2-yloxy)ethoxy]ethanol
CanonicalSMILES C1CCOC(C1)OCCOCCO
InChI InChI=1S/C9H18O4/c10-4-6-11-7-8-13-9-3-1-2-5-12-9/h9-10H,1-8H2
InChIKey CPCUDERUJBARLD-UHFFFAOYSA-N
BoilingPoint 310.3±37.0 °C at 760 mmHg
Purity ≥95%
Density 1.08±0.1 g/cm3
Solubility Soluble in Chloroform (Slightly), Methanol (Slightly)
RelatedCAS 92417-25-9 (polymer) 301295-36-3 (polymer)
PEGType Discrete PEG Linker
PEGArchitecture Linear
Functionality Monofunctional (Reactive)
ProtectingGroup THP
ReactiveToward Activated Carboxyls / Isocyanates
ReactionChemistry Esterification / Carbamate Formation
ResearchUse Ester / Carbamate Formation

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