Tbdms-PEG8-alcohol

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Category	Tbdms-PEGn-alcohol
Catalog NO.	BPG-3476
Product Name	Tbdms-PEG8-alcohol
CAS	1155404-41-3
Molecular Formula	C22H48O9Si
Molecular Weight	484.7

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Description	Tbdms-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It contains a TBDMS alcohol protecting group and a terminal hydroxyl group. TBDMS can be removed in the presence of acetyl chloride. The hydroxyl group can be derived into other compounds by other reactions. The hydrophilic PEG linker can increase the solubility of compounds in aqueous media.
Synonyms	TBDMS-PEG9; TBDMS-PEG8-OH; 2,2,3,3-tetramethyl-4,7,10,13,16,19,22,25-octaoxa-3-silaheptacosan-27-ol
IUPAC Name	2-[2-[2-[2-[2-[2-[2-[2-[tert-butyl(dimethyl)silyl]oxyethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Canonical SMILES	C[Si](OCCOCCOCCOCCOCCOCCOCCOCCO)(C(C)(C)C)C
InChI	InChI=1S/C22H48O9Si/c1-22(2,3)32(4,5)31-21-20-30-19-18-29-17-16-28-15-14-27-13-12-26-11-10-25-9-8-24-7-6-23/h23H,6-21H2,1-5H3
InChIKey	PMWBSWGAQMRFKP-UHFFFAOYSA-N
Purity	≥95%
Storage	Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

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