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t-Boc-N-amido-PEG8-amine

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Category NHBoc-PEGn-amine
Catalog NO. BPG-0565
Product Name t-Boc-N-amido-PEG8-amine
CAS 1052207-59-6
Molecular Formula C23H48N2O10
Molecular Weight 512.64
t-Boc-N-amido-PEG8-amine
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Product Information

Description t-Boc-N-amido-PEG8-amine is a cleavable 8-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms BocNH-PEG8-CH2CH2NH2; NHBoc-PEG8-amine; Boc-NH-PEG8-NH2; Boc-N-amido-PEG8-NH2; tert-Butyl (26-amino-3,6,9,12,15,18,21,24-octaoxahexacosyl)carbamate; 5,8,11,14,17,20,23,26-Octaoxa-2-azaoctacosanoic acid, 28-amino-, 1,1-dimethylethyl ester; 2-Methyl-2-propanyl (26-amino-3,6,9,12,15,18,21,24-octaoxahexacos-1-yl)carbamate; Carbamic acid, N-(26-amino-3,6,9,12,15,18,21,24-octaoxahexacos-1-yl)-, 1,1-dimethylethyl ester
IUPAC Name tert-butyl N-[2-[2-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
Canonical SMILES CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCN
InChI InChI=1S/C23H48N2O10/c1-23(2,3)35-22(26)25-5-7-28-9-11-30-13-15-32-17-19-34-21-20-33-18-16-31-14-12-29-10-8-27-6-4-24/h4-21,24H2,1-3H3,(H,25,26)
InChIKey RJDFELJBUQILOQ-UHFFFAOYSA-N
Boiling Point 579.4±50.0°C at 760 mmHg
Purity ≥95%
Density 1.1±0.1 g/cm3
Solubility Soluble in DCM, DMF, DMSO, Water
Related CAS 890091-42-6 (polymer) 198227-38-2 (polymer)
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C

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PEGylation of Peptides and Proteins

PEGylation of Peptides
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