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t-Boc-N-amido-PEG7-NHS ester

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Category NHBoc-PEGn-NHS ester
Catalog NO. BPG-0575
Product Name t-Boc-N-amido-PEG7-NHS ester
Molecular Formula C26H46N2O13
Molecular Weight 594.66
t-Boc-N-amido-PEG7-NHS ester
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Product Information

Description t-Boc-N-amido-PEG7-NHS ester is a PEG linker containing NHS ester and Boc-protected amine moieties. The Boc group can be deprotected under mildly acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms BocNH-PEG7-CH2CH2COONHS; Boc-N-PEG7-C2-NHS ester; 2,5-dioxopyrrolidin-1-yl 2,2-dimethyl-4-oxo-3,8,11,14,17,20,23,26-octaoxa-5-azanonacosan-29-oate
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCOCCNC(OC(C)(C)C)=O
InChI InChI=1S/C26H46N2O13/c1-26(2,3)40-25(32)27-7-9-34-11-13-36-15-17-38-19-21-39-20-18-37-16-14-35-12-10-33-8-6-24(31)41-28-22(29)4-5-23(28)30/h4-21H2,1-3H3,(H,27,32)
InChIKey YKYCUCKKEPWJRT-UHFFFAOYSA-N
Purity ≥95%
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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