t-Boc-N-amido-PEG2-NHS ester
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Category | NHBoc-PEGn-NHS ester |
Catalog NO. | BPG-0574 |
Product Name | t-Boc-N-amido-PEG2-NHS ester |
CAS | 2183440-73-3 |
Molecular Formula | C16H26N2O8 |
Molecular Weight | 374.39 |
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Description | t-Boc-N-amido-PEG2-NHS ester is a PEG linker containing NHS ester and Boc-protected amine moieties. The Boc group can be deprotected under mildly acidic conditions to form a free amine. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media. |
Synonyms | Boc-NH-PEG2-C2-NHS ester; 2,5-dioxopyrrolidin-1-yl 2,2-dimethyl-4-oxo-3,8,11-trioxa-5-azatetradecan-14-oate; BocNH-PEG2-CH2CH2COONHS; BOC-NH-PEG2-OCH2CH2COONHS Ester; 4,7,12-Trioxa-10-azatetradecanoic acid, 13,13-dimethyl-11-oxo-, 2,5-dioxo-1-pyrrolidinyl ester; 3-[2-(2-tert-Butoxycarbonylamino-ethoxy)-ethoxy]-propionic acid 2,5-dioxopyrrolidin-1-yl ester |
IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethoxy]ethoxy]propanoate |
Canonical SMILES | CC(C)(C)OC(=O)NCCOCCOCCC(=O)ON1C(=O)CCC1=O |
InChI | InChI=1S/C16H26N2O8/c1-16(2,3)25-15(22)17-7-9-24-11-10-23-8-6-14(21)26-18-12(19)4-5-13(18)20/h4-11H2,1-3H3,(H,17,22) |
InChIKey | FNZXIPYAXFROBS-UHFFFAOYSA-N |
Purity | ≥95% |
Density | 1.24±0.1 g/cm3 (Predicted) |
Solubility | Soluble in DCM, DMSO |
Appearance | White Solid |
Storage | Store at 2-8°C |
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