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t-boc-N-amido-PEG2-alcohol

CAS No. CAS No.: 139115-91-6
Cat No. Cat No.: BPG-1752
Purity Purity: ≥95%
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Boc-NH-PEG2 is a PROTAC linker, which refers to the alkyl/ether composition. Boc-NH-PEG2 can be used in the synthesis of a series of PROTACs. Boc-NH-PEG2 is a PEG derivative containing a hydroxyl group and Boc-protected amino group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Category NHBoc-PEGn-OH
Molecular Formula C9H19NO4
Molecular Weight 205.25
Appearance Colorless to Light Orange to Yellow Clear Liquid
Shipping Room temperature in continental US; may vary elsewhere
Storage Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
t-boc-N-amido-PEG2-alcohol

Structure of 139115-91-6

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  • Specification
Synonyms NHBoc-PEG2-OH; N-Boc-PEG2-alcohol; tert-Butyl (2-(2-hydroxyethoxy)ethyl)carbamate; 2-(2-Boc-aminoethoxy)ethanol; [2-(2-Hydroxyethoxy)ethyl]carbamic Acid 1,1-Dimethylethyl Ester; 2-(2-tert-Butoxycarbonylaminoethoxy)ethanol; N-Boc-2-aminoethyl 2-hydroxyethyl Ether; N-[2-(2-Hydroxyethoxy)ethyl]carbamic acid tert-butyl ester; Carbamic acid, N-[2-(2-hydroxyethoxy)ethyl]-, 1,1-dimethylethyl ester; Boc-NH-PEG2
IUPACName tert-butyl N-[2-(2-hydroxyethoxy)ethyl]carbamate
CanonicalSMILES CC(C)(C)OC(=O)NCCOCCO
InChI InChI=1S/C9H19NO4/c1-9(2,3)14-8(12)10-4-6-13-7-5-11/h11H,4-7H2,1-3H3,(H,10,12)
InChIKey KSFVNEXYCULLEJ-UHFFFAOYSA-N
BoilingPoint 332.9±22.0°C (Predicted)
Purity ≥95%
Density 1.061 g/mL at 25°C
Solubility Soluble in Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
RelatedCAS 159156-95-3 (polymer)
ExactMass 205.13140809
LogP 0.91090
Pictogram Acute Toxic, Irritant
Signal Danger
PrecautionaryStatementCodes P264, P264+P265, P270, P280, P301+P316, P302+P352, P305+P351+P338, P321, P330, P332+P317, P337+P317, P362+P364, P405, and P501

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