SPDP-PEG36-COOH

Name: SPDP-PEG36-COOH
Brand: BOC Sciences
Rating: 5 (1 reviews)

Cat No.: BPG-4432

Purity: 0.97

4.5

SPDP-PEG36-acid is a PEG linker containing SPDP crosslinker and carboxylic acid moieties. SPDP is reactive toward thiol groups and contains a cleavable disulfide bond. Its membrane permeability allows for intracellular crosslinking reactions. The terminal caboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic properties of the PEG linkers increase compound solubility in aqueous media. Please contact us for GMP-grade inquiries.

Category	Small-molecule SPDP PEG
Molecular Formula	C83H158N2O39S2
Molecular Weight	1872.3
Shipping	Ambient temperature
Storage	-20°C

Structure of SPDP-PEG36-COOH

Ordering Information

*For research and manufacturing use only. We do not sell to patients.

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Purity

0.97

PEGType	Discrete PEG Linker
PEGArchitecture	Linear
Functionality	Heterobifunctional

ReactiveToward	Thiols; Primary Amines (after activation)
ReactionChemistry	Thiol-Disulfide Exchange; Carbodiimide-Mediated Amide Coupling (EDC/NHS)
BiomoleculeCompatibility	Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides; Proteins / Antibodies; Peptides; Amine-Modified Oligonucleotides
ResearchUse	Reversible Thiol–Disulfide Exchange; Carboxyl-to-Amine Coupling after Activation; Amide Bond Formation