SPDP-PEG24-NHS ester

Name: SPDP-PEG24-NHS ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

Cat No.: BPG-4433

Purity: 0.95

4.5

SPDP-PEG24-NHS ester is a PEG linker containing an SPDP crosslinker and an NHS ester. The SPDP crosslinker is reactive toward amine and thiol groups and contains a cleavable disulfide bond. This crosslinker is also membrane permeable which allows for intracellular reactions to take place. The NHS ester can react with primary amines to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media. Please contact us for GMP-grade inquiries.

Category	Small-molecule SPDP PEG
Molecular Formula	C64H114N2O29S2
Molecular Weight	1439.7
Shipping	Ambient temperature
Storage	-20°C

Structure of SPDP-PEG24-NHS ester

Ordering Information

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Synonyms	SPDP-PEG24-NHS ester; SPDP-dPEG(R)24-NHS ester; alpha-[3-(o-Pyridyldisulfido)propanoylamido]-omega-succinimidyl ester 24(ethylene glycol); MFCD13185007; AKOS030213538; GS-9400; BP-21937; HY-141357
IUPACName	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-(pyridin-2-yldisulfanyl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
CanonicalSMILES	C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCSSC2=CC=CC=N2
InChI	InChI=1S/C63H113N3O29S2/c67-59(7-58-96-97-60-3-1-2-8-65-60)64-9-11-72-13-15-74-17-19-76-21-23-78-25-27-80-29-31-82-33-35-84-37-39-86-41-43-88-45-47-90-49-51-92-53-55-94-57-56-93-54-52-91-50-48-89-46-44-87-42-40-85-38-36-83-34-32-81-30-28-79-26-24-77-22-20-75-18-16-73-14-12-71-10-6-63(70)95-66-61(68)4-5-62(66)69/h1-3,8H,4-7,9-58H2,(H,64,67)
InChIKey	ARLGFRZAOLYVAU-UHFFFAOYSA-N
Purity	0.95

PEGType	Discrete PEG Linker
PEGArchitecture	Linear
Functionality	Heterobifunctional

ReactiveToward	Thiols; Primary Amines
ReactionChemistry	Thiol-Disulfide Exchange; Activated-Ester Amine Coupling
BiomoleculeCompatibility	Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides; Proteins / Antibodies; Peptides; Amine-Modified Oligonucleotides
ResearchUse	Amine-Selective Biomolecule Coupling; Reversible Thiol–Disulfide Exchange