| Category | Propargyl-PEGn-acid |
| Molecular Formula | C10H16O5 |
| Molecular Weight | 216.23 |
| Appearance | Light yellow to brown clear liquid |
| Shipping | Room temperature |
| Storage | Store at -20°C, keep in dry and avoid sunlight |
Propargyl-PEG3-acid
Propargyl-PEG3-acid is an alkyne-functionalized ADC linker with a carboxyl terminus for amide coupling. Its PEG spacer enhances solubility and flexibility in antibody-drug conjugates, facilitating click chemistry-based bioconjugation strategies.
Structure of 1347760-82-0
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- Specification
| Synonyms | 3-(2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethoxy)propanoic acid; Propyne-PEG2-CH2CH2COOH; Alkyne-PEG3-COOH; Propargyl-PEG3-COOH; Propargyl-PEG3-Carboxylic Acid; 3-[2-[2-(2-Propyn-1-yloxy)ethoxy]ethoxy]propanoic acid; Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]- |
| IUPACName | 3-[2-(2-prop-2-ynoxyethoxy)ethoxy]propanoic acid |
| CanonicalSMILES | C#CCOCCOCCOCCC(=O)O |
| InChI | InChI=1S/C10H16O5/c1-2-4-13-6-8-15-9-7-14-5-3-10(11)12/h1H,3-9H2,(H,11,12) |
| InChIKey | CJNSWLAJTZVSRB-UHFFFAOYSA-N |
| BoilingPoint | 348.0±32.0 °C at 760 mmHg |
| FlashPoint | 131.8±18.6 °C |
| Purity | >98.0% |
| Density | 1.1±0.1 g/cm3 |
| Solubility | Soluble in DCM, DMF, DMSO, Water |
| ShelfLife | ≥ 2 years |
| VaporPressure | 0.0±1.6 mmHg at 25°C |
| LogP | -0.44 |
| Pictogram | Irritant |
| Signal | Warning |
| PrecautionaryStatementCodes | P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 |
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