| Category | Small-molecule Carboxylic Acid PEG |
| Molecular Formula | C21H16F9NO5S |
| Molecular Weight | 565.41 |
| Storage | Store at -20 °C |
PFB-mercaptopropionyl-AEEA
PFB-mercaptopropionyl-AEEA is a linker for π-Clamp-mediated site-selective cysteine conjugation, enabling precise modification of peptides or proteins at specific sites. It combines a perfluorobiphenyl (PFB) group, a mercaptopropionyl moiety, and an AEEA spacer, facilitating stable thiol-reactive coupling and enhanced solubility for bioconjugation applications.
Structure of PFB-mercaptopropionyl-AEEA
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- Specification
| Synonyms | Perfluorobiphenyl-mercaptopropionyl-AEEA |
| IUPACName | 2-(2-(2-(3-((perfluoro-[1,1'-biphenyl]-4-yl)thio)propanamido)ethoxy)ethoxy)acetic acid |
| CanonicalSMILES | O=C(O)COCCOCCNC(CCSC1=C(F)C(F)=C(C2=C(F)C(F)=C(F)C(F)=C2F)C(F)=C1F)=O |
| InChI | InChI=1S/C21H16F9NO5S/c22-12-10(13(23)17(27)18(28)16(12)26)11-14(24)19(29)21(20(30)15(11)25)37-6-1-8(32)31-2-3-35-4-5-36-7-9(33)34/h1-7H2,(H,31,32)(H,33,34) |
| InChIKey | QMLZWFVHQJKAIL-UHFFFAOYSA-N |
| Purity | >98% |
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