PFB-mercaptopropionyl-AEEA

Name: PFB-mercaptopropionyl-AEEA
Brand: BOC Sciences
Rating: 5 (1 reviews)

Cat No.: BPG-4844

Purity: >98%

4.5

PFB-mercaptopropionyl-AEEA is a linker for π-Clamp-mediated site-selective cysteine conjugation, enabling precise modification of peptides or proteins at specific sites. It combines a perfluorobiphenyl (PFB) group, a mercaptopropionyl moiety, and an AEEA spacer, facilitating stable thiol-reactive coupling and enhanced solubility for bioconjugation applications.

Category	Small-molecule Carboxylic Acid PEG
Molecular Formula	C21H16F9NO5S
Molecular Weight	565.41
Storage	Store at -20 °C

Structure of PFB-mercaptopropionyl-AEEA

Ordering Information

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Synonyms	Perfluorobiphenyl-mercaptopropionyl-AEEA
IUPACName	2-(2-(2-(3-((perfluoro-[1,1'-biphenyl]-4-yl)thio)propanamido)ethoxy)ethoxy)acetic acid
CanonicalSMILES	O=C(O)COCCOCCNC(CCSC1=C(F)C(F)=C(C2=C(F)C(F)=C(F)C(F)=C2F)C(F)=C1F)=O
InChI	InChI=1S/C21H16F9NO5S/c22-12-10(13(23)17(27)18(28)16(12)26)11-14(24)19(29)21(20(30)15(11)25)37-6-1-8(32)31-2-3-35-4-5-36-7-9(33)34/h1-7H2,(H,31,32)(H,33,34)
InChIKey	QMLZWFVHQJKAIL-UHFFFAOYSA-N
Purity	>98%

PEGType	PEG / Oligoethylene Glycol Building Block
PEGArchitecture	Linear
Functionality	Monofunctional (Reactive)

ReactiveToward	Primary Amines (after activation)
ReactionChemistry	Carbodiimide-Mediated Amide Coupling (EDC/NHS)
BiomoleculeCompatibility	Proteins / Antibodies; Peptides; Amine-Modified Oligonucleotides
ResearchUse	Carboxyl-to-Amine Coupling after Activation; Amide Bond Formation