NHPI-PEG4-C2-NHS ester

Name: NHPI-PEG4-C2-NHS ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 1415328-95-8

Cat No.: BPG-3600

Purity: 98%

4.5

NHPI-PEG4-C2-NHS ester is a PEG-based spacer and synthetic linker building block used to introduce a defined hydrophilic and flexible segment into multistep conjugation designs. The PEG chain can increase molecular spacing and provide a modular connection between reactive groups without serving as a dedicated cleavage trigger. This derivative contains peg4 spacer together with terminal functionality selected for further synthesis. The available reactive group is nhs/succinimidyl ester (amine-reactive) for antibody lysines/primary amines. The opposite terminus provides terminal peg functionality depends on the specific derivative; additional activation may be required. Coupling and deprotection conditions should be matched to the terminal groups and the intended order of assembly.

Category	NHPI-PEGn-C2-NHS ester
Molecular Formula	C23H28N2O11
Molecular Weight	508.48
Appearance	Pale Yellow or Colorless Oily Matter
Shipping	Room temperature
Storage	Store at 2-8°C

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Specification

Synonyms	2,5-dioxopyrrolidin-1-yl 1-(1,3-dioxoisoindolin-2-yloxy)-3,6,9,12-tetraoxapentadecan-15-oate; Phthalimidooxy-PEG4-NHS ester; 4,7,10,13-Tetraoxapentadecanoic acid acid, 15-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-, 2,5-dioxo-1-pyrrolidinyl ester; 1H-Isoindole-1,3(2H)-dione, 2-[[15-[(2,5-dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl]oxy]-; 2-({15-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-15-oxo-3,6,9,12-tetraoxapentadec-1-yl}oxy)-1H-isoindole-1,3(2H)-dione
IUPACName	(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-(1,3-dioxoisoindol-2-yl)oxyethoxy]ethoxy]ethoxy]ethoxy]propanoate
CanonicalSMILES	C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCOCCON2C(=O)C3=CC=CC=C3C2=O
InChI	InChI=1S/C23H28N2O11/c26-19-5-6-20(27)24(19)36-21(28)7-8-31-9-10-32-11-12-33-13-14-34-15-16-35-25-22(29)17-3-1-2-4-18(17)23(25)30/h1-4H,5-16H2
InChIKey	HLAGLPXQSIDIDX-UHFFFAOYSA-N
BoilingPoint	638.5±65.0°C at 760 mmHg
Purity	98%
Density	1.4±0.1 g/cm3
Solubility	Soluble in DMSO