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NHPI-PEG3-C2-NHS ester

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Category NHPI-PEGn-C2-NHS ester
Catalog NO. BPG-0586
Product Name NHPI-PEG3-C2-NHS ester
CAS 2101206-14-6
Molecular Formula C21H24N2O10
Molecular Weight 464.42
NHPI-PEG3-C2-NHS ester
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Product Information

Description NHPI-PEG3-C2-NHS ester is a non-cleavable 3-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs).
Synonyms Phthalimidooxy-PEG3-NHS ester; Propanoic acid, 3-[2-[2-[2-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]ethoxy]ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester; 2-{2-[2-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethoxy)ethoxy]ethoxy}-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 2-[2-[2-[2-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]-; 2,5-Dioxopyrrolidin-1-yl 3-(2-(2-(2-(1,3-dioxoisoindolin-2-yloxy)ethoxy)ethoxy)ethoxy)propanoate
IUPAC Name (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-(1,3-dioxoisoindol-2-yl)oxyethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES C1CC(=O)N(C1=O)OC(=O)CCOCCOCCOCCON2C(=O)C3=CC=CC=C3C2=O
InChI InChI=1S/C21H24N2O10/c24-17-5-6-18(25)22(17)33-19(26)7-8-29-9-10-30-11-12-31-13-14-32-23-20(27)15-3-1-2-4-16(15)21(23)28/h1-4H,5-14H2
InChIKey OWAQXTSIBSTPOX-UHFFFAOYSA-N
Boiling Point 612.6±65.0°C at 760 mmHg
Purity ≥95%
Density 1.4±0.1 g/cm3
Solubility Soluble in DMSO
Storage Store at 2-8°C

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PEGylation of Peptides and Proteins

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