N-(Mal-PEG4)-N-bis(PEG4-N-Boc)

Name: N-(Mal-PEG4)-N-bis(PEG4-N-Boc)
Brand: BOC Sciences
Rating: 5 (1 reviews)

Cat No.: BPG-4338

Purity: 0.97

4.5

N-(Mal-PEG4)-N-bis(PEG4-N-Boc) is a trifunctional linker with two Boc-protected amines and a maleimide group. Maleimide is a site-specific covalent linker which easily reacts with thiol groups via a simple Michael addition. The amines can be easily deprotected using acidic conditions to allow for coupling with carboxylic acids in the presence of an activator like HATU. The junction combining these functional groups is a tertiary amide, which is highly water soluble through hydrogen bonding effects.

Category	Small-molecule Maleimide PEG
Molecular Formula	C48H87N5O20
Molecular Weight	1054.3
Shipping	Ambient temperature
Storage	-20°C

Structure of N-(Mal-PEG4)-N-bis(PEG4-N-Boc)

Ordering Information

*For research and manufacturing use only. We do not sell to patients.

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Purity

0.97

PEGType	Multi-Arm PEG
PEGArchitecture	3-Arm
Functionality	Homobifunctional
ProtectingGroup	Boc

ReactiveToward	Thiols
ReactionChemistry	Maleimide-Thiol Conjugation
BiomoleculeCompatibility	Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides
ResearchUse	Thiol-Selective Biomolecule Conjugation; Multivalent Hydrogel / Polymer Crosslinking