Mono-Sulfone NHS Ester

Name: Mono-Sulfone NHS Ester
Brand: BOC Sciences
Rating: 5 (1 reviews)

Cat No.: BPG-4396

4.5

Mono-sulfone is a thiol-specific labeling reagent that undergo alkylation to generate a thio-ether bond between the protein and mono-sulfone activated reagent. Once mono-sulfone reagent is conjugated to a protein or peptide, exchange reactions leading to deconjugation can be easily avoided by treating the conjugate with a mild reducing agent in a way analogous to the process used for conjugation reactions involving reductive amination.

Category	Small-molecule NHS ester PEG
Molecular Formula	C21H19NO7S
Molecular Weight	429.5
Shipping	Ambient temperature
Storage	-20°C

Structure of Mono-Sulfone NHS Ester

Ordering Information

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Specification

Synonyms	Mono-sulfone NHS Ester; SCHEMBL23734429
IUPACName	(2,5-dioxopyrrolidin-1-yl) 4-[3-(4-methylphenyl)sulfonylpropanoyl]benzoate
CanonicalSMILES	CC1=CC=C(C=C1)S(=O)(=O)CCC(=O)C2=CC=C(C=C2)C(=O)ON3C(=O)CCC3=O
InChI	InChI=1S/C21H19NO7S/c1-14-2-8-17(9-3-14)30(27,28)13-12-18(23)15-4-6-16(7-5-15)21(26)29-22-19(24)10-11-20(22)25/h2-9H,10-13H2,1H3
InChIKey	VVJCBWILSDVJOO-UHFFFAOYSA-N