| Category | Mal-PEGn-acid |
| Molecular Formula | C11H15NO6 |
| Molecular Weight | 257.24 |
| Appearance | White to Light Yellow Powder to Crystal |
| Shipping | Room temperature, or blue ice upon request. |
| Storage | Store at 2-8°C |
Mal-PEG2-acid
Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-acid can be conjugated to Tubulysin (HY-128914) and its derivative cytotoxic molecule.
Structure of 1374666-32-6
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- Specification
| Synonyms | Mal-PEG2-CH2CH2COOH; Maleimide-PEG2-CH2CH2COOH; Mal-PEG2-COOH; Mal-PEG2-propionic acid; 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoic acid; Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]- |
| IUPACName | 3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoic acid |
| CanonicalSMILES | C1=CC(=O)N(C1=O)CCOCCOCCC(=O)O |
| InChI | InChI=1S/C11H15NO6/c13-9-1-2-10(14)12(9)4-6-18-8-7-17-5-3-11(15)16/h1-2H,3-8H2,(H,15,16) |
| InChIKey | TXMDOUPVKVGPIS-UHFFFAOYSA-N |
| BoilingPoint | 455.7±35.0 °C at 760 mmHg |
| FlashPoint | 229.4±25.9 °C |
| Purity | ≥95% |
| Density | 1.329±0.06 g/cm3 (Predicted) |
| Solubility | Soluble in DMSO (10 mm) |
| RelatedCAS | <a href="/product/mal-peg12-acid-cas-357277-61-3-448974.html">357277-61-3</a> (polymer) 2422928-26-3 (polymer) |
| ShelfLife | 0-4°C for short term (days to weeks), or -20°C for long term (months). |
| VaporPressure | 0.0±2.4 mmHg at 25°C |
| LogP | -0.73 |
| Pictogram | Irritant |
| Signal | Warning |
| PrecautionaryStatementCodes | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
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