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Mal-amido-PEG12-TFP ester

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Category Mal-amido-PEGn-TFP ester
Catalog NO. BPG-0329
Product Name Mal-amido-PEG12-TFP ester
Molecular Formula C40H60F4N2O17
Molecular Weight 916.91
Mal-amido-PEG12-TFP ester
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Product Information

Description Mal-amido-PEG12-TFP ester is a PEG linker containing a maleimide and TFP ester end group. The Maleimide group is reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chain increases the water solubility of a compound in aqueous media.
Synonyms Mal-NH-PEG12-TFP; MAL-PEG12-TFP ester; MAL-dPEG12-TFP ester; 2,3,5,6-tetrafluorophenyl 1-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-oxo-7,10,13,16,19,22,25,28,31,34,37,40-dodecaoxa-4-azatritetracontan-43-oate
IUPAC Name (2,3,5,6-tetrafluorophenyl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES O=C(OC1=C(F)C(F)=CC(F)=C1F)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O
InChI InChI=1S/C40H60F4N2O17/c41-32-31-33(42)39(44)40(38(32)43)63-37(50)4-7-51-9-11-53-13-15-55-17-19-57-21-23-59-25-27-61-29-30-62-28-26-60-24-22-58-20-18-56-16-14-54-12-10-52-8-5-45-34(47)3-6-46-35(48)1-2-36(46)49/h1-2,31H,3-30H2,(H,45,47)
InChIKey TYRMHYMPAXBKTH-UHFFFAOYSA-N
Purity ≥95%
Storage Store at 2-8°C

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