Mal-amido-PEG10-acid

Name: Mal-amido-PEG10-acid
Brand: BOC Sciences
Rating: 5 (1 reviews)

CAS No.: 2785355-74-8

Cat No.: BPG-4349

Purity: 0.97

4.5

Mal-amido-PEG10-acid is a PEG linker containing a maleimide group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. Please contact us for GMP-grade inquiries.

Category	Small-molecule Maleimide PEG
Molecular Formula	C30H52N2O15
Molecular Weight	680.8
Shipping	Ambient temperature
Storage	-20°C

Structure of 2785355-74-8

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Specification
Key Product Attributes
Reaction & Conjugation Properties

Synonyms	Mal-amido-PEG10-acid; Maleimide-NH-PEG10-CH2CH2COOH; 2785355-74-8; SCHEMBL24512047; EX-A8185R; AKOS040743509; BP-22984; HY-140973
IUPACName	3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
CanonicalSMILES	C1=CC(=O)N(C1=O)CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O
InChI	InChI=1S/C30H52N2O15/c33-27(3-6-32-28(34)1-2-29(32)35)31-5-8-39-10-12-41-14-16-43-18-20-45-22-24-47-26-25-46-23-21-44-19-17-42-15-13-40-11-9-38-7-4-30(36)37/h1-2H,3-26H2,(H,31,33)(H,36,37)
InChIKey	OWNIWXFZMUNTGE-UHFFFAOYSA-N
Purity	0.97

PEGType	Discrete PEG Linker
PEGArchitecture	Linear
Functionality	Heterobifunctional

ReactiveToward	Thiols; Primary Amines (after activation)
ReactionChemistry	Maleimide-Thiol Conjugation; Carbodiimide-Mediated Amide Coupling (EDC/NHS)
BiomoleculeCompatibility	Thiol-Bearing Proteins / Antibodies; Cysteine-Containing Peptides; Thiol-Modified Oligonucleotides; Proteins / Antibodies; Peptides; Amine-Modified Oligonucleotides
ResearchUse	Thiol-Selective Biomolecule Conjugation; Carboxyl-to-Amine Coupling after Activation; Amide Bond Formation