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Lipoamido-PEG11-acid
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| Category | Lipoamido-PEGn-acid |
| Catalog NO. | BPG-0288 |
| Product Name | Lipoamido-PEG11-acid |
| Molecular Formula | C33H63NO14S2 |
| Molecular Weight | 761.98 |
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| Description | Lipoamido-PEG11-acid is a PEG linker containing a lipoic acid group and a terminal carboxylic acid. Lipoic acid contains two sulfur atoms (at C6 and C8) connected by a disulfide bond and is thus considered to be oxidized although either sulfur atom can exist in higher oxidation states. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG linker increases the water solubility of the compound. |
| Synonyms | Lipoamido-PEG11-CH2CH2COOH; 42-(1,2-dithiolan-3-yl)-38-oxo-4,7,10,13,16,19,22,25,28,31,34-undecaoxa-37-azadotetracontanoic acid |
| IUPAC Name | 3-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(5-(1,2-dithiolan-3-yl)pentanamido)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)propanoic acid |
| Canonical SMILES | O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCCC1SSCC1)=O |
| InChI | InChI=1S/C33H63NO14S2/c35-32(4-2-1-3-31-6-30-49-50-31)34-7-9-39-11-13-41-15-17-43-19-21-45-23-25-47-27-29-48-28-26-46-24-22-44-20-18-42-16-14-40-12-10-38-8-5-33(36)37/h31H,1-30H2,(H,34,35)(H,36,37) |
| InChIKey | WSFXYCUPJONHPC-UHFFFAOYSA-N |
| Purity | ≥95% |
| Related CAS | 1334172-71-2 (polymer) |
| Storage | Store at 2-8°C |
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Technical Information
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Industry News
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- Lipid Classification and Drug Delivery Systems
- Lipid Formulations: Key Absorption-Enhancing Technologies in New Drug Development
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- Overview of Liposome Preparation Process
- PEG in Pharmaceutical Preparations (I): Solvents, Lubricants, Adhesives and More
- PEG in Pharmaceutical Preparations (II): Stabilizers, Plasticizers and Modification Materials
- PEG Linkers in Antibody Drug Conjugates and PROTACs
- PEG-DSPE Block Copolymers and Their Derivatives
- PEGylated Drugs: Definition, Structure, Classification and Benefits
- PEGylated RGD Peptides: A Promising Tool for Targeted Drug Delivery
- Pharmacokinetics and Bioanalysis of PEGylated Drugs
- Polyethylene Glycol (PEG) Modified Targeting Nanomaterials
- Preparation Method of PEG Hydrogel
- The PROTAC Technology in Drug Development
- Vaccines: Definition, History, Ingredients, Types and Mechanism of Action
- What are Lipid Excipients and Their Applications?
- What are Lipid Nanoparticles and Their Applications?
- What are Lipid-Drug Conjugates (LDCs)?
- What are Lipids?
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