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Hydroxy-PEG5-acid

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Category HO-PEGn-COOH
Catalog NO. BPG-0645
Product Name Hydroxy-PEG5-acid
CAS 2079768-50-4
Molecular Formula C13H26O8
Molecular Weight 310.34
Hydroxy-PEG5-acid
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Product Information

Description Hydroxy-PEG5-acid is a non-cleavable 5-unit PEG linker that can be used to synthesize antibody-conjugated drugs (ADCs).
Synonyms OH-PEG5-COOH; HO-PEG5-Propionic acid; HO-PEG5-CH2CH2COOH; Hydroxy-PEG5-propionic acid; 1-Hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oic acid; Propanoic acid, 3-[(14-hydroxy-3,6,9,12-tetraoxatetradec-1-yl)oxy]-; 3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-hydroxy-
IUPAC Name 3-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES C(COCCOCCOCCOCCOCCO)C(=O)O
InChI InChI=1S/C13H26O8/c14-2-4-18-6-8-20-10-12-21-11-9-19-7-5-17-3-1-13(15)16/h14H,1-12H2,(H,15,16)
InChIKey NQZLSNLBIKBFNP-UHFFFAOYSA-N
Boiling Point 455.7±45.0°C at 760 mmHg
Purity ≥95%
Density 1.2±0.1 g/cm3
Solubility Soluble in DMSO
Appearance Pale Yellow or Colorless Oily Matter
Storage Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)

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PEGylation of Peptides and Proteins

PEGylation of Peptides
and Proteins

Reduce the Immunogenicity of Peptide/Protein Drugs

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PEG linkers For Drug

Improved Circulation Half-Life

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