| Category | Small-molecule Alkyne PEG |
| Molecular Formula | C28H34F5NO8 |
| Molecular Weight | 607.6 |
| Shipping | Ambient temperature |
| Storage | -20°C |
endo-BCN-PEG4-PFP ester
endo-BCN-PEG4-PFP ester is a click chemistry reagent containing a PFP ester and a BCN group. PFP esters have similar applications as the NHS esters, but are more stable in aqueous solution. They can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The BCN group cais reactive with azide-tagged molecules. The hydrophilic PEG spacer increases solubility in aqueous media. Please contact us for GMP-grade inquiries.
Structure of 2904607-26-5
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- Specification
- Key Product Attributes
- Reaction & Conjugation Properties
| Synonyms | endo-BCN-PEG4-PFP ester; 1421932-52-6; perfluorophenyl 1-(bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oate; 2,3,4,5,6-pentafluorophenyl 1-{[({bicyclo[6.1.0]non-4-yn-9-yl}methoxy)carbonyl]amino}-3,6,9,12-tetraoxapentadecan-15-oate; Exo-BCN-PEG4-PFP ester; ENDO-BCN-PEG4-PFPESTER; SCHEMBL17776276; 2904607-26-5 |
| IUPACName | (2,3,4,5,6-pentafluorophenyl) 3-[2-[2-[2-[2-(9-bicyclo[6.1.0]non-4-ynylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoate |
| CanonicalSMILES | C1CC2C(C2COC(=O)NCCOCCOCCOCCOCCC(=O)OC3=C(C(=C(C(=C3F)F)F)F)F)CCC#C1 |
| InChI | InChI=1S/C28H34F5NO8/c29-22-23(30)25(32)27(26(33)24(22)31)42-21(35)7-9-37-11-13-39-15-16-40-14-12-38-10-8-34-28(36)41-17-20-18-5-3-1-2-4-6-19(18)20/h18-20H,3-17H2,(H,34,36) |
| InChIKey | SWBZFLVGZRZGCI-UHFFFAOYSA-N |
| Purity | 0.95 |
| PEGType | Discrete PEG Linker |
| PEGArchitecture | Linear |
| Functionality | Heterobifunctional |
| ReactiveToward | Primary Amines; Azides |
| ReactionChemistry | Activated-Ester Amine Coupling; SPAAC Click Chemistry |
| BiomoleculeCompatibility | Proteins / Antibodies; Peptides; Amine-Modified Oligonucleotides; Click-Handle-Modified Proteins / Peptides; Click-Handle-Modified Antibodies; Click-Handle-Modified Oligonucleotides; Small Molecules / Probes |
| ResearchUse | Copper-Free Azide–Cyclooctyne Ligation; Amine-Selective Biomolecule Coupling |
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