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COOH-PEG6-COOtBu

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Category	COOH-PEGn-COOtBu
Catalog NO.	BPG-1563
Product Name	COOH-PEG6-COOtBu
CAS	2093153-84-3
Molecular Formula	C20H38O10
Molecular Weight	438.51

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Description	COOH-PEG6-COOtBu is a PEG linker containing a t-butyl-protected carboxyl group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The t-butyl-protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
Synonyms	Acid-PEG6-t-butyl ester; Acid-PEG6-C2-Boc; HOOCCH2CH2O-PEG5-CH2CH2COOtBu; COOH-PEG6-OtBu; 2,2-Dimethyl-4-oxo-3,7,10,13,16,19,22-heptaoxapentacosan-25-oic acid; 4,7,10,13,16,19-Hexaoxadocosane-1,22-dioic acid, mono(1,1-dimethylethyl) ester
IUPAC Name	3-[2-[2-[2-[2-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
Canonical SMILES	CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCC(=O)O
InChI	InChI=1S/C20H38O10/c1-20(2,3)30-19(23)5-7-25-9-11-27-13-15-29-17-16-28-14-12-26-10-8-24-6-4-18(21)22/h4-17H2,1-3H3,(H,21,22)
InChIKey	HHEKCKLYBRNNLN-UHFFFAOYSA-N
Boiling Point	528.9±50.0°C at 760 mmHg
Purity	≥95%
Density	1.1±0.1 g/cm3
Solubility	Soluble in DCM, DMF, DMSO, Water
Appearance	Pale Yellow or Colorless Oily Matter
Storage	Store at 2-8°C

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