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CHO-Ph-CONH-PEG8-COOtBu

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Category	CHO-Ph-CONH-PEGn-COOtBu
Catalog NO.	BPG-1477
Product Name	CHO-Ph-CONH-PEG8-COOtBu
Molecular Formula	C31H51NO12
Molecular Weight	629.74

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Description	CHO-Ph-CONH-PEG8-COOtBu contains a benzaldehyde group that can react with aminooxy (ONH2) bearing molecules. The t-butyl ester is a protecting group that can be removed under acidic conditions for further conjugation. The hydrophilic PEG linker increases the water solubility of the compound.
Synonyms	Ald-Ph-PEG8-t-butyl ester; DF-PEG8-CH2CH2COOtBu; Ald-Ph-amido-PEG8-C2-Boc; Ald-Ph-PEG8-CH2CH2COOtBu; Ald-Ph-PEG8-COOtBu; tert-butyl 1-(4-formylphenyl)-1-oxo-5,8,11,14,17,20,23,26-octaoxa-2-azanonacosan-29-oate
IUPAC Name	tert-butyl 3-[2-[2-[2-[2-[2-[2-[2-[2-[(4-formylbenzoyl)amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
Canonical SMILES	O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(C1=CC=C(C=O)C=C1)=O
InChI	InChI=1S/C31H51NO12/c1-31(2,3)44-29(34)8-10-36-12-14-38-16-18-40-20-22-42-24-25-43-23-21-41-19-17-39-15-13-37-11-9-32-30(35)28-6-4-27(26-33)5-7-28/h4-7,26H,8-25H2,1-3H3,(H,32,35)
InChIKey	RYIZDXPBNQSTPO-UHFFFAOYSA-N
Purity	≥95%
Storage	Store at 2-8°C

CHO-Ph-CONH-PEG8-COOtBu, a versatile chemical compound with a myriad of biomedical and biotechnological applications, stands at the forefront of cutting-edge research. Here are four key applications of CHO-Ph-CONH-PEG8-COOtBu:

Drug Delivery: Nestled at the core of innovative drug delivery systems lies CHO-Ph-CONH-PEG8-COOtBu, a compound that excels in orchestrating targeted therapies. Its unique PEGylation property not only bolsters the solubility and stability of drugs, but also extends their circulation time in the bloodstream.

Bioconjugation: Central to bioconjugation techniques is the indispensable CHO-Ph-CONH-PEG8-COOtBu, a key player in affixing biomolecules like peptides, proteins, and antibodies onto diverse surfaces or carriers. The PEG chain's pivotal role in mitigating nonspecific binding and immunogenic reactions elevates the biocompatibility of the resultant conjugates.

Surface Modification: In the realm of biomaterials and medical devices, CHO-Ph-CONH-PEG8-COOtBu reigns supreme as a potent surface modifier, elevating biocompatibility and functional attributes. By enveloping implants or sensors with this compound, researchers effectively diminish protein adsorption and cell adhesion, thereby minimizing the potential for immune reactions and biofouling. This transformation translates into prolonged performance and heightened reliability of medical implants and biosensors, underscoring the critical role of CHO-Ph-CONH-PEG8-COOtBu in advancing healthcare technologies.

Analytical Chemistry: In the domain of analytical chemistry, CHO-Ph-CONH-PEG8-COOtBu emerges as a key player in the development of sophisticated chromatographic systems and surface plasmon resonance (SPR) sensors. Leveraging its PEGylation prowess, this compound enhances the separation and detection of biomolecules by mitigating nonspecific interactions.

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