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BP Lipid 221

Cat No. Cat No.: BPG-3638
Purity Purity: 0.98
4.5 Reviews Start

BP Lipid 221 is an ionizable amino lipid which has both ester bonds located adjacent to C7 relative to the nitogen amine. This lipid is an analogous to BP-25498/ALC-0315. The head contains butanolamine which can efficiently encapsulate mRNA. The lipid can be used to prepare mRNA nanocarriers with good balance of delivery efficiency and pharmakokinetics as well as rapid lipid clearance profile. Please contact us for GMP-grade inquiries.

Category ALC-0315 & Analogs
Molecular Formula C50H99NO5
Molecular Weight 794.4
Shipping Ambient temperature
Storage -20°C
BP Lipid 221

Structure of BP Lipid 221

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  • Specification
Synonyms BP Lipid 221; ((4-Hydroxybutyl)azanediyl)bis(heptane-7,1-diyl) bis(2-hexyldecanoate); SCHEMBL25410189; BP-27898; CS-0435790
IUPACName 7-[7-(2-hexyldecanoyloxy)heptyl-(4-hydroxybutyl)amino]heptyl 2-hexyldecanoate
CanonicalSMILES CCCCCCCCC(CCCCCC)C(=O)OCCCCCCCN(CCCCCCCOC(=O)C(CCCCCC)CCCCCCCC)CCCCO
InChI InChI=1S/C50H99NO5/c1-5-9-13-17-21-29-39-47(37-27-15-11-7-3)49(53)55-45-35-25-19-23-31-41-51(43-33-34-44-52)42-32-24-20-26-36-46-56-50(54)48(38-28-16-12-8-4)40-30-22-18-14-10-6-2/h47-48,52H,5-46H2,1-4H3
InChIKey FREVKFZVQDKSNH-UHFFFAOYSA-N
Purity 0.98

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